null

SMILES: CC(C)(C)OC(=O)N1C[C@H](C[C@H]1C(=O)N[C@@H](Cc1ccc(O[Si](C)(C)C(C)(C)C)cc1)C(=O)NS(=O)(=O)c1ccc(Cl)c(c1)[N+]([O-])=O)Oc1ccc(cc1)-c1ccccc1

InChI Key: InChIKey=NGGZJFYOGNLBNZ-BQKXBGLYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50206480   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Induced myeloid leukemia cell differentiation protein Mcl-1 (Homo sapiens (Human))	BDBM50206480 (CHEMBL3962531) Show SMILES CC(C)(C)OC(=O)N1C[C@H](C[C@H]1C(=O)N[C@@H](Cc1ccc(O[Si](C)(C)C(C)(C)C)cc1)C(=O)NS(=O)(=O)c1ccc(Cl)c(c1)[N+]([O-])=O)Oc1ccc(cc1)-c1ccccc1 |r| Show InChI InChI=1S/C43H51ClN4O10SSi/c1-42(2,3)57-41(51)47-27-33(56-31-20-16-30(17-21-31)29-12-10-9-11-13-29)25-38(47)40(50)45-36(24-28-14-18-32(19-15-28)58-60(7,8)43(4,5)6)39(49)46-59(54,55)34-22-23-35(44)37(26-34)48(52)53/h9-23,26,33,36,38H,24-25,27H2,1-8H3,(H,45,50)(H,46,49)/t33-,36-,38-/m0/s1	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	77	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Shandong University Curated by ChEMBL					Assay Description Inhibition of 5-FAM-QEDIIRNIARHLAQVGDSMDRSIPPG binding to Mcl-1 (unknown origin) preincubated for 30 mins followed by FAM-labeled peptide addition me...				Bioorg Med Chem 25: 138-152 (2017) Article DOI: 10.1016/j.bmc.2016.10.020 BindingDB Entry DOI: 10.7270/Q2P84DWQ
					More data for this Ligand-Target Pair
Bcl-2-like protein 1 (Homo sapiens (Human))	BDBM50206480 (CHEMBL3962531) Show SMILES CC(C)(C)OC(=O)N1C[C@H](C[C@H]1C(=O)N[C@@H](Cc1ccc(O[Si](C)(C)C(C)(C)C)cc1)C(=O)NS(=O)(=O)c1ccc(Cl)c(c1)[N+]([O-])=O)Oc1ccc(cc1)-c1ccccc1 |r| Show InChI InChI=1S/C43H51ClN4O10SSi/c1-42(2,3)57-41(51)47-27-33(56-31-20-16-30(17-21-31)29-12-10-9-11-13-29)25-38(47)40(50)45-36(24-28-14-18-32(19-15-28)58-60(7,8)43(4,5)6)39(49)46-59(54,55)34-22-23-35(44)37(26-34)48(52)53/h9-23,26,33,36,38H,24-25,27H2,1-8H3,(H,45,50)(H,46,49)/t33-,36-,38-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Shandong University Curated by ChEMBL					Assay Description Inhibition of 5-FAM-DMRPEIWIAQELRRIGDEFNAYYARR binding to Bcl-XL (unknown origin) preincubated for 30 mins followed by FAM-labeled peptide addition m...				Bioorg Med Chem 25: 138-152 (2017) Article DOI: 10.1016/j.bmc.2016.10.020 BindingDB Entry DOI: 10.7270/Q2P84DWQ
					More data for this Ligand-Target Pair
Apoptosis regulator Bcl-2 (Homo sapiens (Human))	BDBM50206480 (CHEMBL3962531) Show SMILES CC(C)(C)OC(=O)N1C[C@H](C[C@H]1C(=O)N[C@@H](Cc1ccc(O[Si](C)(C)C(C)(C)C)cc1)C(=O)NS(=O)(=O)c1ccc(Cl)c(c1)[N+]([O-])=O)Oc1ccc(cc1)-c1ccccc1 |r| Show InChI InChI=1S/C43H51ClN4O10SSi/c1-42(2,3)57-41(51)47-27-33(56-31-20-16-30(17-21-31)29-12-10-9-11-13-29)25-38(47)40(50)45-36(24-28-14-18-32(19-15-28)58-60(7,8)43(4,5)6)39(49)46-59(54,55)34-22-23-35(44)37(26-34)48(52)53/h9-23,26,33,36,38H,24-25,27H2,1-8H3,(H,45,50)(H,46,49)/t33-,36-,38-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	930	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Shandong University Curated by ChEMBL					Assay Description Inhibition of 5-FAM-QEDIIRNIARHLAQVGDSMDRSIPPG binding to Bcl-2 (unknown origin) preincubated for 30 mins followed by FAM-labeled peptide addition me...				Bioorg Med Chem 25: 138-152 (2017) Article DOI: 10.1016/j.bmc.2016.10.020 BindingDB Entry DOI: 10.7270/Q2P84DWQ
					More data for this Ligand-Target Pair