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SMILES: CN([C@H]1CCN(C1)C1CCOCC1)C(=O)N1CC[C@@H](C1)n1cnc2cc(sc2c1=O)-c1ccc(cc1)C(F)(F)F

InChI Key: InChIKey=COXWWZLQFCHTMQ-VXKWHMMOSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50206688   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Melanin-concentrating hormone receptor 1


(Homo sapiens (Human))		BDBM50206688
PNG
((S)-N-methyl-3-(4-oxo-6-(4-(trifluoromethyl)phenyl...)
Show SMILES CN([C@H]1CCN(C1)C1CCOCC1)C(=O)N1CC[C@@H](C1)n1cnc2cc(sc2c1=O)-c1ccc(cc1)C(F)(F)F
Show InChI InChI=1S/C28H32F3N5O3S/c1-33(21-6-10-34(15-21)20-8-12-39-13-9-20)27(38)35-11-7-22(16-35)36-17-32-23-14-24(40-25(23)26(36)37)18-2-4-19(5-3-18)28(29,30)31/h2-5,14,17,20-22H,6-13,15-16H2,1H3/t21-,22-/m0/s1
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Similars
Article
PubMed
 19n/an/an/an/an/an/an/an/a



Neurocrine Biosciences Inc.

Curated by ChEMBL


Assay Description
Binding affinity to human MCHR1

Bioorg Med Chem Lett 17: 2535-9 (2007)


Article DOI: 10.1016/j.bmcl.2007.02.012
BindingDB Entry DOI: 10.7270/Q23778CV
More data for this
Ligand-Target Pair