BDBM50206908 (+/-)-1-O-(4-cyanomethylphenyl)-3-O-[4-(4,5-dihydro-5-oxo-1,2,4-4H-oxadiazol-3-yl)methylphenyl]-2-O-tetradecylglycerol::CHEMBL373870

SMILES: CCCCCCCCCCCCCCOC(COCc1ccc(cc1)C#N)COc1ccc(Cc2nc(=O)o[nH]2)cc1

InChI Key: InChIKey=AJHQQNUVUCZRJN-UHFFFAOYSA-N

Data: 6 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50206908   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Secretory phospholipase A2, group V (sPLA2-V) (Homo sapiens (Human))	BDBM50206908 ((+/-)-1-O-(4-cyanomethylphenyl)-3-O-[4-(4,5-dihydr...) Show SMILES CCCCCCCCCCCCCCOC(COCc1ccc(cc1)C#N)COc1ccc(Cc2nc(=O)o[nH]2)cc1 Show InChI InChI=1S/C34H47N3O5/c1-2-3-4-5-6-7-8-9-10-11-12-13-22-40-32(26-39-25-30-16-14-29(24-35)15-17-30)27-41-31-20-18-28(19-21-31)23-33-36-34(38)42-37-33/h14-21,32H,2-13,22-23,25-27H2,1H3,(H,36,37,38)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.73E+3	n/a	n/a	n/a	n/a	n/a	n/a
Université Paris7-Denis Diderot Curated by ChEMBL					Assay Description Inhibition of human group V PLA2 in [3H]oleate-labeled Escherichia coli membrane by radiometric assay				J Med Chem 50: 1618-26 (2007) Article DOI: 10.1021/jm060082n BindingDB Entry DOI: 10.7270/Q2TQ6174
					More data for this Ligand-Target Pair
Phospholipase A2, membrane associated (Homo sapiens (Human))	BDBM50206908 ((+/-)-1-O-(4-cyanomethylphenyl)-3-O-[4-(4,5-dihydr...) Show SMILES CCCCCCCCCCCCCCOC(COCc1ccc(cc1)C#N)COc1ccc(Cc2nc(=O)o[nH]2)cc1 Show InChI InChI=1S/C34H47N3O5/c1-2-3-4-5-6-7-8-9-10-11-12-13-22-40-32(26-39-25-30-16-14-29(24-35)15-17-30)27-41-31-20-18-28(19-21-31)23-33-36-34(38)42-37-33/h14-21,32H,2-13,22-23,25-27H2,1H3,(H,36,37,38)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Université Paris7-Denis Diderot Curated by ChEMBL					Assay Description Inhibition of human group IIA PLA2 in [3H]oleate-labeled Escherichia coli membrane by radiometric assay				J Med Chem 50: 1618-26 (2007) Article DOI: 10.1021/jm060082n BindingDB Entry DOI: 10.7270/Q2TQ6174
					More data for this Ligand-Target Pair
Phospholipase A2, major isoenzyme (Sus scrofa (pig))	BDBM50206908 ((+/-)-1-O-(4-cyanomethylphenyl)-3-O-[4-(4,5-dihydr...) Show SMILES CCCCCCCCCCCCCCOC(COCc1ccc(cc1)C#N)COc1ccc(Cc2nc(=O)o[nH]2)cc1 Show InChI InChI=1S/C34H47N3O5/c1-2-3-4-5-6-7-8-9-10-11-12-13-22-40-32(26-39-25-30-16-14-29(24-35)15-17-30)27-41-31-20-18-28(19-21-31)23-33-36-34(38)42-37-33/h14-21,32H,2-13,22-23,25-27H2,1H3,(H,36,37,38)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Université Paris7-Denis Diderot Curated by ChEMBL					Assay Description Inhibition of pig group IB PLA2 by fluorimetric assay				J Med Chem 50: 1618-26 (2007) Article DOI: 10.1021/jm060082n BindingDB Entry DOI: 10.7270/Q2TQ6174
					More data for this Ligand-Target Pair
Phospholipase A2 (Homo sapiens (Human))	BDBM50206908 ((+/-)-1-O-(4-cyanomethylphenyl)-3-O-[4-(4,5-dihydr...) Show SMILES CCCCCCCCCCCCCCOC(COCc1ccc(cc1)C#N)COc1ccc(Cc2nc(=O)o[nH]2)cc1 Show InChI InChI=1S/C34H47N3O5/c1-2-3-4-5-6-7-8-9-10-11-12-13-22-40-32(26-39-25-30-16-14-29(24-35)15-17-30)27-41-31-20-18-28(19-21-31)23-33-36-34(38)42-37-33/h14-21,32H,2-13,22-23,25-27H2,1H3,(H,36,37,38)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Université Paris7-Denis Diderot Curated by ChEMBL					Assay Description Inhibition of human group IB PLA2 in [3H]oleate-labeled Escherichia coli membrane by radiometric assay				J Med Chem 50: 1618-26 (2007) Article DOI: 10.1021/jm060082n BindingDB Entry DOI: 10.7270/Q2TQ6174
					More data for this Ligand-Target Pair
Phospholipase A2, membrane associated (Homo sapiens (Human))	BDBM50206908 ((+/-)-1-O-(4-cyanomethylphenyl)-3-O-[4-(4,5-dihydr...) Show SMILES CCCCCCCCCCCCCCOC(COCc1ccc(cc1)C#N)COc1ccc(Cc2nc(=O)o[nH]2)cc1 Show InChI InChI=1S/C34H47N3O5/c1-2-3-4-5-6-7-8-9-10-11-12-13-22-40-32(26-39-25-30-16-14-29(24-35)15-17-30)27-41-31-20-18-28(19-21-31)23-33-36-34(38)42-37-33/h14-21,32H,2-13,22-23,25-27H2,1H3,(H,36,37,38)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Université Paris7-Denis Diderot Curated by ChEMBL					Assay Description Inhibition of human group IIA PLA2 by fluorimetric assay				J Med Chem 50: 1618-26 (2007) Article DOI: 10.1021/jm060082n BindingDB Entry DOI: 10.7270/Q2TQ6174
					More data for this Ligand-Target Pair
Group X secretory phospholipase A2 (Homo sapiens (Human))	BDBM50206908 ((+/-)-1-O-(4-cyanomethylphenyl)-3-O-[4-(4,5-dihydr...) Show SMILES CCCCCCCCCCCCCCOC(COCc1ccc(cc1)C#N)COc1ccc(Cc2nc(=O)o[nH]2)cc1 Show InChI InChI=1S/C34H47N3O5/c1-2-3-4-5-6-7-8-9-10-11-12-13-22-40-32(26-39-25-30-16-14-29(24-35)15-17-30)27-41-31-20-18-28(19-21-31)23-33-36-34(38)42-37-33/h14-21,32H,2-13,22-23,25-27H2,1H3,(H,36,37,38)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Université Paris7-Denis Diderot Curated by ChEMBL					Assay Description Inhibition of human group X PLA2 in [3H]oleate-labeled Escherichia coli membrane by radiometric assay				J Med Chem 50: 1618-26 (2007) Article DOI: 10.1021/jm060082n BindingDB Entry DOI: 10.7270/Q2TQ6174
					More data for this Ligand-Target Pair