BDBM50206953 CHEMBL3982975

SMILES: [H][C@@]12CC[C@@](O)(C#CC)[C@@]1(C)C[C@H](OC(=O)OCC=C)[C@]1([H])c3ccc(cc3CC[C@@]21[H])C(=O)Nc1cccnc1C

InChI Key: InChIKey=FTLJWKUZWUDXMD-VJRZSFLMSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50206953   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50206953 (CHEMBL3982975) Show SMILES [H][C@@]12CC[C@@](O)(C#CC)[C@@]1(C)C[C@H](OC(=O)OCC=C)[C@]1([H])c3ccc(cc3CC[C@@]21[H])C(=O)Nc1cccnc1C |r| Show InChI InChI=1S/C32H36N2O5/c1-5-14-32(37)15-13-25-24-12-9-21-18-22(29(35)34-26-8-7-16-33-20(26)3)10-11-23(21)28(24)27(19-31(25,32)4)39-30(36)38-17-6-2/h6-8,10-11,16,18,24-25,27-28,37H,2,9,12-13,15,17,19H2,1,3-4H3,(H,34,35)/t24-,25-,27-,28+,31-,32-/m0/s1	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	84	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Antagonist activity at GR in human HepG2 cells assessed as inhibition of protein mediated-transcriptional activity by MMTV-promoter driven luciferase...				Bioorg Med Chem Lett 27: 347-353 (2017) Article DOI: 10.1016/j.bmcl.2016.11.007 BindingDB Entry DOI: 10.7270/Q24B339Q
					More data for this Ligand-Target Pair