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SMILES: OC(=O)COc1c(Br)c(Br)sc1C(=O)Nc1nccs1

InChI Key: InChIKey=CZVCTKKYRCTJRK-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50206996   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Tyrosine-protein phosphatase non-receptor type 1


(Homo sapiens (Human))		BDBM50206996
PNG
(2-(4,5-dibromo-2-(thiazol-2-ylcarbamoyl)thiophen-3...)
Show SMILES OC(=O)COc1c(Br)c(Br)sc1C(=O)Nc1nccs1
Show InChI InChI=1S/C10H6Br2N2O4S2/c11-5-6(18-3-4(15)16)7(20-8(5)12)9(17)14-10-13-1-2-19-10/h1-2H,3H2,(H,15,16)(H,13,14,17)
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MMDB

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PC cid
PC sid
UniChem
Article
PubMed
n/an/a>2.50E+6n/an/an/an/an/an/a



Wyeth Research

Curated by ChEMBL


Assay Description
Inhibition of PTP1B assessed as pNPP hydrolysis

Bioorg Med Chem Lett 17: 2913-20 (2007)


Article DOI: 10.1016/j.bmcl.2007.02.043
BindingDB Entry DOI: 10.7270/Q29S1QPC
More data for this
Ligand-Target Pair