BindingDB logo
myBDB logout

null

SMILES: NNC(=O)c1sc(Br)c(Br)c1OCC(O)=O

InChI Key: InChIKey=CRLBGLOAHWZJBZ-UHFFFAOYSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50207010   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Tyrosine-protein phosphatase non-receptor type 1


(Homo sapiens (Human))		BDBM50207010
PNG
(CHEMBL239577 | {[4,5-dibromo-2-(hydrazinocarbonyl)...)
Show SMILES NNC(=O)c1sc(Br)c(Br)c1OCC(O)=O
Show InChI InChI=1S/C7H6Br2N2O4S/c8-3-4(15-1-2(12)13)5(7(14)11-10)16-6(3)9/h1,10H2,(H,11,14)(H,12,13)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a>2.50E+6n/an/an/an/an/an/a



Wyeth Research

Curated by ChEMBL


Assay Description
Inhibition of PTP1B assessed as pNPP hydrolysis

Bioorg Med Chem Lett 17: 2913-20 (2007)


Article DOI: 10.1016/j.bmcl.2007.02.043
BindingDB Entry DOI: 10.7270/Q29S1QPC
More data for this
Ligand-Target Pair