BDBM50207165 4-morpholin-4-yl-2-phenyl-pyrido[3',2':4,5]furo[3,2-d]pyrimidine::CHEMBL388480

SMILES: C1CN(CCO1)c1nc(nc2c3cccnc3oc12)-c1ccccc1

InChI Key: InChIKey=NVQCHUVXJRWAFQ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50207165   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens (Human))	BDBM50207165 (4-morpholin-4-yl-2-phenyl-pyrido[3',2':4,5]furo[3,...) Show SMILES C1CN(CCO1)c1nc(nc2c3cccnc3oc12)-c1ccccc1 Show InChI InChI=1S/C19H16N4O2/c1-2-5-13(6-3-1)17-21-15-14-7-4-8-20-19(14)25-16(15)18(22-17)23-9-11-24-12-10-23/h1-8H,9-12H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	160	n/a	n/a	n/a	n/a	n/a	n/a
Astellas Pharma Inc. Curated by ChEMBL					Assay Description Inhibition of p110alpha by SPA assay				Bioorg Med Chem Lett 17: 2438-42 (2007) Article DOI: 10.1016/j.bmcl.2007.02.032 BindingDB Entry DOI: 10.7270/Q28053F2
					More data for this Ligand-Target Pair