BDBM50207169 4-(4-morpholin-4-yl-pyrido[3',2':4,5]furo[3,2-d]pyrimidin-2-yl)-phenol hydrochloride::CHEMBL541906

SMILES: Oc1ccc(cc1)-c1nc(N2CCOCC2)c2oc3ncccc3c2n1

InChI Key: InChIKey=CCCHXFXRXKOQKH-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50207169   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens (Human))	BDBM50207169 (4-(4-morpholin-4-yl-pyrido[3',2':4,5]furo[3,2-d]py...) Show SMILES Oc1ccc(cc1)-c1nc(N2CCOCC2)c2oc3ncccc3c2n1 Show InChI InChI=1S/C19H16N4O3/c24-13-5-3-12(4-6-13)17-21-15-14-2-1-7-20-19(14)26-16(15)18(22-17)23-8-10-25-11-9-23/h1-7,24H,8-11H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	26	n/a	n/a	n/a	n/a	n/a	n/a
Astellas Pharma Inc. Curated by ChEMBL					Assay Description Inhibition of p110alpha by SPA assay				Bioorg Med Chem Lett 17: 2438-42 (2007) Article DOI: 10.1016/j.bmcl.2007.02.032 BindingDB Entry DOI: 10.7270/Q28053F2
					More data for this Ligand-Target Pair