BDBM50207170 2-(3-methoxy-phenyl)-4-morpholin-4-yl-pyrido[3',2':4,5]furo[3,2-d]pyrimidine hydrochloride::CHEMBL537877

SMILES: COc1cccc(c1)-c1nc(N2CCOCC2)c2oc3ncccc3c2n1

InChI Key: InChIKey=JIXRGOVACNEBTD-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50207170   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens (Human))	BDBM50207170 (2-(3-methoxy-phenyl)-4-morpholin-4-yl-pyrido[3',2'...) Show SMILES COc1cccc(c1)-c1nc(N2CCOCC2)c2oc3ncccc3c2n1 Show InChI InChI=1S/C20H18N4O3/c1-25-14-5-2-4-13(12-14)18-22-16-15-6-3-7-21-20(15)27-17(16)19(23-18)24-8-10-26-11-9-24/h2-7,12H,8-11H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Astellas Pharma Inc. Curated by ChEMBL					Assay Description Inhibition of p110alpha by SPA assay				Bioorg Med Chem Lett 17: 2438-42 (2007) Article DOI: 10.1016/j.bmcl.2007.02.032 BindingDB Entry DOI: 10.7270/Q28053F2
					More data for this Ligand-Target Pair