BDBM50207496 CHEMBL373435::N-{1-methyl-4-[4-(3-methylphenylureido)phenyl]-1H-indazol-3-yl}acetamide

SMILES: CC(=O)Nc1nn(C)c2cccc(-c3ccc(NC(=O)Nc4cccc(C)c4)cc3)c12

InChI Key: InChIKey=OHFKUABCVXNBNC-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50207496   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50207496 (CHEMBL373435 | N-{1-methyl-4-[4-(3-methylphenylure...) Show SMILES CC(=O)Nc1nn(C)c2cccc(-c3ccc(NC(=O)Nc4cccc(C)c4)cc3)c12 Show InChI InChI=1S/C24H23N5O2/c1-15-6-4-7-19(14-15)27-24(31)26-18-12-10-17(11-13-18)20-8-5-9-21-22(20)23(25-16(2)30)28-29(21)3/h4-14H,1-3H3,(H,25,28,30)(H2,26,27,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of VEGF-induced human KDR phosphorylation in mouse 3T3 cells by ELISA				J Med Chem 50: 1584-97 (2007) Article DOI: 10.1021/jm061280h BindingDB Entry DOI: 10.7270/Q2DJ5F95
					More data for this Ligand-Target Pair