BDBM50207508 CHEMBL219999::N-{4-[3-amino-1-(2-hydroxyethyl)-1H-indazol-4-yl]phenyl}-N'-(3-methylphenyl)urea

SMILES: Cc1cccc(NC(=O)Nc2ccc(cc2)-c2cccc3n(CCO)nc(N)c23)c1

InChI Key: InChIKey=GRWZZLSYMYWWDR-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50207508   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50207508 (CHEMBL219999 | N-{4-[3-amino-1-(2-hydroxyethyl)-1H...) Show SMILES Cc1cccc(NC(=O)Nc2ccc(cc2)-c2cccc3n(CCO)nc(N)c23)c1 Show InChI InChI=1S/C23H23N5O2/c1-15-4-2-5-18(14-15)26-23(30)25-17-10-8-16(9-11-17)19-6-3-7-20-21(19)22(24)27-28(20)12-13-29/h2-11,14,29H,12-13H2,1H3,(H2,24,27)(H2,25,26,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of VEGF-induced human KDR phosphorylation in mouse 3T3 cells by ELISA				J Med Chem 50: 1584-97 (2007) Article DOI: 10.1021/jm061280h BindingDB Entry DOI: 10.7270/Q2DJ5F95
					More data for this Ligand-Target Pair
Receptor-type tyrosine-protein kinase FLT3 (Homo sapiens (Human))	BDBM50207508 (CHEMBL219999 | N-{4-[3-amino-1-(2-hydroxyethyl)-1H...) Show SMILES Cc1cccc(NC(=O)Nc2ccc(cc2)-c2cccc3n(CCO)nc(N)c23)c1 Show InChI InChI=1S/C23H23N5O2/c1-15-4-2-5-18(14-15)26-23(30)25-17-10-8-16(9-11-17)19-6-3-7-20-21(19)22(24)27-28(20)12-13-29/h2-11,14,29H,12-13H2,1H3,(H2,24,27)(H2,25,26,30)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	270	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of FLT3 by HTRF assay				J Med Chem 50: 1584-97 (2007) Article DOI: 10.1021/jm061280h BindingDB Entry DOI: 10.7270/Q2DJ5F95
					More data for this Ligand-Target Pair