BDBM50207511 1-(4-(3-amino-1-(2-(diethylamino)ethoxy)-1H-indazol-4-yl)phenyl)-3-(2-fluoro-5-methylphenyl)urea::CHEMBL221574

SMILES: CCN(CC)CCOn1nc(N)c2c(cccc12)-c1ccc(NC(=O)Nc2cc(C)ccc2F)cc1

InChI Key: InChIKey=OWCONRLOJMQZQS-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50207511   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50207511 (1-(4-(3-amino-1-(2-(diethylamino)ethoxy)-1H-indazo...) Show SMILES CCN(CC)CCOn1nc(N)c2c(cccc12)-c1ccc(NC(=O)Nc2cc(C)ccc2F)cc1 Show InChI InChI=1S/C27H31FN6O2/c1-4-33(5-2)15-16-36-34-24-8-6-7-21(25(24)26(29)32-34)19-10-12-20(13-11-19)30-27(35)31-23-17-18(3)9-14-22(23)28/h6-14,17H,4-5,15-16H2,1-3H3,(H2,29,32)(H2,30,31,35)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of VEGF-induced human KDR phosphorylation in mouse 3T3 cells by ELISA				J Med Chem 50: 1584-97 (2007) Article DOI: 10.1021/jm061280h BindingDB Entry DOI: 10.7270/Q2DJ5F95
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50207511 (1-(4-(3-amino-1-(2-(diethylamino)ethoxy)-1H-indazo...) Show SMILES CCN(CC)CCOn1nc(N)c2c(cccc12)-c1ccc(NC(=O)Nc2cc(C)ccc2F)cc1 Show InChI InChI=1S/C27H31FN6O2/c1-4-33(5-2)15-16-36-34-24-8-6-7-21(25(24)26(29)32-34)19-10-12-20(13-11-19)30-27(35)31-23-17-18(3)9-14-22(23)28/h6-14,17H,4-5,15-16H2,1-3H3,(H2,29,32)(H2,30,31,35)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	74	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of KDR by HTRF assay				J Med Chem 50: 1584-97 (2007) Article DOI: 10.1021/jm061280h BindingDB Entry DOI: 10.7270/Q2DJ5F95
					More data for this Ligand-Target Pair