BDBM50207672 CHEMBL248295::N-(1-(3-fluoro-4-(2-(pyrrolidin-1-yl)ethoxy)benzyl)piperidin-4-yl)-7-fluoro-4-oxo-4H-chromene-2-carboxamide

SMILES: Fc1ccc2c(c1)oc(cc2=O)C(=O)NC1CCN(Cc2ccc(OCCN3CCCC3)c(F)c2)CC1

InChI Key: InChIKey=HLZNAQVCWPQRSV-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50207672   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanin-concentrating hormone receptor (Homo sapiens (Human))	BDBM50207672 (CHEMBL248295 | N-(1-(3-fluoro-4-(2-(pyrrolidin-1-y...) Show SMILES Fc1ccc2c(c1)oc(cc2=O)C(=O)NC1CCN(Cc2ccc(OCCN3CCCC3)c(F)c2)CC1 Show InChI InChI=1S/C28H31F2N3O4/c29-20-4-5-22-24(34)17-27(37-26(22)16-20)28(35)31-21-7-11-33(12-8-21)18-19-3-6-25(23(30)15-19)36-14-13-32-9-1-2-10-32/h3-6,15-17,21H,1-2,7-14,18H2,(H,31,35)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Antagonist activity at MCHR1 assessed as inhibition of MCH-mediated calcium release in IMR32 cells				Bioorg Med Chem Lett 17: 2365-71 (2007) Article DOI: 10.1016/j.bmcl.2006.11.068 BindingDB Entry DOI: 10.7270/Q2N29WNW
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor (Homo sapiens (Human))	BDBM50207672 (CHEMBL248295 | N-(1-(3-fluoro-4-(2-(pyrrolidin-1-y...) Show SMILES Fc1ccc2c(c1)oc(cc2=O)C(=O)NC1CCN(Cc2ccc(OCCN3CCCC3)c(F)c2)CC1 Show InChI InChI=1S/C28H31F2N3O4/c29-20-4-5-22-24(34)17-27(37-26(22)16-20)28(35)31-21-7-11-33(12-8-21)18-19-3-6-25(23(30)15-19)36-14-13-32-9-1-2-10-32/h3-6,15-17,21H,1-2,7-14,18H2,(H,31,35)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.52E+3	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Displacement of [125I]MCH from MCHR1 expressed in IMR32 cells				Bioorg Med Chem Lett 17: 2365-71 (2007) Article DOI: 10.1016/j.bmcl.2006.11.068 BindingDB Entry DOI: 10.7270/Q2N29WNW
					More data for this Ligand-Target Pair