null

SMILES: COc1cc(ccc1CN1CCC(CC1)NC(=O)c1cc(=O)c2ccc(F)cc2o1)C(=O)NCCN1CCCC1

InChI Key: InChIKey=DMGSWCYGFARROW-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50207673   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50207673 (CHEMBL246259 | N-(1-(2-methoxy-4-((2-(pyrrolidin-1...) Show SMILES COc1cc(ccc1CN1CCC(CC1)NC(=O)c1cc(=O)c2ccc(F)cc2o1)C(=O)NCCN1CCCC1 Show InChI InChI=1S/C30H35FN4O5/c1-39-26-16-20(29(37)32-10-15-34-11-2-3-12-34)4-5-21(26)19-35-13-8-23(9-14-35)33-30(38)28-18-25(36)24-7-6-22(31)17-27(24)40-28/h4-7,16-18,23H,2-3,8-15,19H2,1H3,(H,32,37)(H,33,38)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	270	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Antagonist activity at MCHR1 assessed as inhibition of MCH-mediated calcium release in IMR32 cells				Bioorg Med Chem Lett 17: 2365-71 (2007) Article DOI: 10.1016/j.bmcl.2006.11.068 BindingDB Entry DOI: 10.7270/Q2N29WNW
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50207673 (CHEMBL246259 | N-(1-(2-methoxy-4-((2-(pyrrolidin-1...) Show SMILES COc1cc(ccc1CN1CCC(CC1)NC(=O)c1cc(=O)c2ccc(F)cc2o1)C(=O)NCCN1CCCC1 Show InChI InChI=1S/C30H35FN4O5/c1-39-26-16-20(29(37)32-10-15-34-11-2-3-12-34)4-5-21(26)19-35-13-8-23(9-14-35)33-30(38)28-18-25(36)24-7-6-22(31)17-27(24)40-28/h4-7,16-18,23H,2-3,8-15,19H2,1H3,(H,32,37)(H,33,38)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	26	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Displacement of [125I]MCH from MCHR1 expressed in IMR32 cells				Bioorg Med Chem Lett 17: 2365-71 (2007) Article DOI: 10.1016/j.bmcl.2006.11.068 BindingDB Entry DOI: 10.7270/Q2N29WNW
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50207673 (CHEMBL246259 | N-(1-(2-methoxy-4-((2-(pyrrolidin-1...) Show SMILES COc1cc(ccc1CN1CCC(CC1)NC(=O)c1cc(=O)c2ccc(F)cc2o1)C(=O)NCCN1CCCC1 Show InChI InChI=1S/C30H35FN4O5/c1-39-26-16-20(29(37)32-10-15-34-11-2-3-12-34)4-5-21(26)19-35-13-8-23(9-14-35)33-30(38)28-18-25(36)24-7-6-22(31)17-27(24)40-28/h4-7,16-18,23H,2-3,8-15,19H2,1H3,(H,32,37)(H,33,38)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]dofetilide from hERG expressed in HEK293 cell membrane				Bioorg Med Chem Lett 17: 2365-71 (2007) Article DOI: 10.1016/j.bmcl.2006.11.068 BindingDB Entry DOI: 10.7270/Q2N29WNW
					More data for this Ligand-Target Pair