BDBM50207678 CHEMBL247891::N-(1-(4-(3-(dicyclopropylamino)propoxy)-3-fluorobenzyl)piperidin-4-yl)-7-fluoro-4-oxo-4H-chromene-2-carboxamide

SMILES: Fc1ccc2c(c1)oc(cc2=O)C(=O)NC1CCN(Cc2ccc(OCCCN(C3CC3)C3CC3)c(F)c2)CC1

InChI Key: InChIKey=AMVUYMPRVIDZMG-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50207678   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50207678 (CHEMBL247891 | N-(1-(4-(3-(dicyclopropylamino)prop...) Show SMILES Fc1ccc2c(c1)oc(cc2=O)C(=O)NC1CCN(Cc2ccc(OCCCN(C3CC3)C3CC3)c(F)c2)CC1 Show InChI InChI=1S/C31H35F2N3O4/c32-21-3-8-25-27(37)18-30(40-29(25)17-21)31(38)34-22-10-13-35(14-11-22)19-20-2-9-28(26(33)16-20)39-15-1-12-36(23-4-5-23)24-6-7-24/h2-3,8-9,16-18,22-24H,1,4-7,10-15,19H2,(H,34,38)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	740	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]dofetilide from hERG expressed in HEK293 cell membrane				Bioorg Med Chem Lett 17: 2365-71 (2007) Article DOI: 10.1016/j.bmcl.2006.11.068 BindingDB Entry DOI: 10.7270/Q2N29WNW
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor (Homo sapiens (Human))	BDBM50207678 (CHEMBL247891 | N-(1-(4-(3-(dicyclopropylamino)prop...) Show SMILES Fc1ccc2c(c1)oc(cc2=O)C(=O)NC1CCN(Cc2ccc(OCCCN(C3CC3)C3CC3)c(F)c2)CC1 Show InChI InChI=1S/C31H35F2N3O4/c32-21-3-8-25-27(37)18-30(40-29(25)17-21)31(38)34-22-10-13-35(14-11-22)19-20-2-9-28(26(33)16-20)39-15-1-12-36(23-4-5-23)24-6-7-24/h2-3,8-9,16-18,22-24H,1,4-7,10-15,19H2,(H,34,38)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.01E+3	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Antagonist activity at MCHR1 assessed as inhibition of MCH-mediated calcium release in IMR32 cells				Bioorg Med Chem Lett 17: 2365-71 (2007) Article DOI: 10.1016/j.bmcl.2006.11.068 BindingDB Entry DOI: 10.7270/Q2N29WNW
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor (Homo sapiens (Human))	BDBM50207678 (CHEMBL247891 | N-(1-(4-(3-(dicyclopropylamino)prop...) Show SMILES Fc1ccc2c(c1)oc(cc2=O)C(=O)NC1CCN(Cc2ccc(OCCCN(C3CC3)C3CC3)c(F)c2)CC1 Show InChI InChI=1S/C31H35F2N3O4/c32-21-3-8-25-27(37)18-30(40-29(25)17-21)31(38)34-22-10-13-35(14-11-22)19-20-2-9-28(26(33)16-20)39-15-1-12-36(23-4-5-23)24-6-7-24/h2-3,8-9,16-18,22-24H,1,4-7,10-15,19H2,(H,34,38)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	51	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Displacement of [125I]MCH from MCHR1 expressed in IMR32 cells				Bioorg Med Chem Lett 17: 2365-71 (2007) Article DOI: 10.1016/j.bmcl.2006.11.068 BindingDB Entry DOI: 10.7270/Q2N29WNW
					More data for this Ligand-Target Pair