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BDBM50207680 CHEMBL247283::N-(1-(3-fluoro-4-(2-morpholinoethoxy)benzyl)piperidin-4-yl)-7-fluoro-4-oxo-4H-chromene-2-carboxamide

SMILES: Fc1ccc2c(c1)oc(cc2=O)C(=O)NC1CCN(Cc2ccc(OCCN3CCOCC3)c(F)c2)CC1

InChI Key: InChIKey=CRHMTDYCSHOAOU-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50207680   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Melanin-concentrating hormone receptor


(Homo sapiens (Human))
BDBM50207680
PNG
(CHEMBL247283 | N-(1-(3-fluoro-4-(2-morpholinoethox...)
Show SMILES Fc1ccc2c(c1)oc(cc2=O)C(=O)NC1CCN(Cc2ccc(OCCN3CCOCC3)c(F)c2)CC1
Show InChI InChI=1S/C28H31F2N3O5/c29-20-2-3-22-24(34)17-27(38-26(22)16-20)28(35)31-21-5-7-33(8-6-21)18-19-1-4-25(23(30)15-19)37-14-11-32-9-12-36-13-10-32/h1-4,15-17,21H,5-14,18H2,(H,31,35)
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PC cid
PC sid
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Similars

Article
PubMed
n/an/a>2.00E+3n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Displacement of [125I]MCH from MCHR1 expressed in IMR32 cells


Bioorg Med Chem Lett 17: 2365-71 (2007)


Article DOI: 10.1016/j.bmcl.2006.11.068
BindingDB Entry DOI: 10.7270/Q2N29WNW
More data for this
Ligand-Target Pair