BDBM50207806 31-(dimethylamino)-5,15,25,30-tetraazaheptacyclo[27.2.2.1^{5,12}.1^{18,25}.0^{6,11}.0^{13,17}.0^{19,24}]pentatriaconta-1(31),6(11),7,9,12(35),13(17),18(34),19(24),20,22,29,32-dodecaene-14,16-dione::CHEMBL392167

SMILES: CN(C)c1nc2CCCn3cc(C4=C(C(=O)NC4=O)c4cn(CCCc1cc2)c1ccccc41)c1ccccc31

InChI Key: InChIKey=RBUVCVIKSPNSSA-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50207806   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM50207806 (31-(dimethylamino)-5,15,25,30-tetraazaheptacyclo[2...) Show SMILES CN(C)c1nc2CCCn3cc(C4=C(C(=O)NC4=O)c4cn(CCCc1cc2)c1ccccc41)c1ccccc31 |t:12| Show InChI InChI=1S/C33H31N5O2/c1-36(2)31-21-9-7-17-37-19-25(23-11-3-5-13-27(23)37)29-30(33(40)35-32(29)39)26-20-38(28-14-6-4-12-24(26)28)18-8-10-22(34-31)16-15-21/h3-6,11-16,19-20H,7-10,17-18H2,1-2H3,(H,35,39,40)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	37	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL					Assay Description Inhibition of human recombinant GSK3-beta				Bioorg Med Chem Lett 17: 2863-8 (2007) Article DOI: 10.1016/j.bmcl.2007.02.059 BindingDB Entry DOI: 10.7270/Q2SF2X1M
					More data for this Ligand-Target Pair