BDBM50207807 31-(pyrrolidin-1-yl)-5,15,25,30-tetraazaheptacyclo[27.2.2.1^{5,12}.1^{18,25}.0^{6,11}.0^{13,17}.0^{19,24}]pentatriaconta-1(31),6(11),7,9,12(35),13(17),18(34),19(24),20,22,29,32-dodecaene-14,16-dione::CHEMBL396327

SMILES: O=C1NC(=O)C2=C1c1cn(CCCc3ccc(CCCn4cc2c2ccccc42)c(n3)N2CCCC2)c2ccccc12

InChI Key: InChIKey=YFLNNYYLWMIKLH-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50207807   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
PKC alpha and beta-2 (Homo sapiens (Human))	BDBM50207807 (31-(pyrrolidin-1-yl)-5,15,25,30-tetraazaheptacyclo...) Show SMILES O=C1NC(=O)C2=C1c1cn(CCCc3ccc(CCCn4cc2c2ccccc42)c(n3)N2CCCC2)c2ccccc12 |c:5| Show InChI InChI=1S/C35H33N5O2/c41-34-31-27-21-39(29-13-3-1-11-25(27)29)19-7-9-23-15-16-24(36-33(23)38-17-5-6-18-38)10-8-20-40-22-28(32(31)35(42)37-34)26-12-2-4-14-30(26)40/h1-4,11-16,21-22H,5-10,17-20H2,(H,37,41,42)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL					Assay Description Inhibition of human recombinant PKCbeta2				Bioorg Med Chem Lett 17: 2863-8 (2007) Article DOI: 10.1016/j.bmcl.2007.02.059 BindingDB Entry DOI: 10.7270/Q2SF2X1M
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM50207807 (31-(pyrrolidin-1-yl)-5,15,25,30-tetraazaheptacyclo...) Show SMILES O=C1NC(=O)C2=C1c1cn(CCCc3ccc(CCCn4cc2c2ccccc42)c(n3)N2CCCC2)c2ccccc12 |c:5| Show InChI InChI=1S/C35H33N5O2/c41-34-31-27-21-39(29-13-3-1-11-25(27)29)19-7-9-23-15-16-24(36-33(23)38-17-5-6-18-38)10-8-20-40-22-28(32(31)35(42)37-34)26-12-2-4-14-30(26)40/h1-4,11-16,21-22H,5-10,17-20H2,(H,37,41,42)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL					Assay Description Inhibition of human recombinant GSK3-beta				Bioorg Med Chem Lett 17: 2863-8 (2007) Article DOI: 10.1016/j.bmcl.2007.02.059 BindingDB Entry DOI: 10.7270/Q2SF2X1M
					More data for this Ligand-Target Pair