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SMILES: Cc1cccc(N2CCN(CC(O)COc3cccc(c3)C(=O)CCc3ccccc3)CC2)c1C

InChI Key: InChIKey=ASNAPVUCVQMNNL-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50207920   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
ATP-dependent translocase ABCB1


(Homo sapiens (Human))		BDBM50207920
PNG
(1-(3-(3-(4-(2,3-dimethylphenyl)piperazin-1-yl)-2-h...)
Show SMILES Cc1cccc(N2CCN(CC(O)COc3cccc(c3)C(=O)CCc3ccccc3)CC2)c1C
Show InChI InChI=1S/C30H36N2O3/c1-23-8-6-13-29(24(23)2)32-18-16-31(17-19-32)21-27(33)22-35-28-12-7-11-26(20-28)30(34)15-14-25-9-4-3-5-10-25/h3-13,20,27,33H,14-19,21-22H2,1-2H3
PDB

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/an/an/a 137n/an/an/an/a



University of Vienna

Curated by ChEMBL


Assay Description
Inhibition of P-glycoprotein expressed in MDR CCRF vcr1000 cells by daunorubicin efflux assay

J Med Chem 50: 1698-702 (2007)


Article DOI: 10.1021/jm060604z
BindingDB Entry DOI: 10.7270/Q2SB46JC
More data for this
Ligand-Target Pair