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SMILES: CC(=O)c1ccc(OCC(O)CN2CCN(CC2)c2cccc(C)c2C)cc1

InChI Key: InChIKey=KQZDGQRWGREOJP-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50207924   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
ATP-dependent translocase ABCB1


(Homo sapiens (Human))		BDBM50207924
PNG
(1-(4-(3-(4-(2,3-dimethylphenyl)piperazin-1-yl)-2-h...)
Show SMILES CC(=O)c1ccc(OCC(O)CN2CCN(CC2)c2cccc(C)c2C)cc1
Show InChI InChI=1S/C23H30N2O3/c1-17-5-4-6-23(18(17)2)25-13-11-24(12-14-25)15-21(27)16-28-22-9-7-20(8-10-22)19(3)26/h4-10,21,27H,11-16H2,1-3H3
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antibodypedia
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UniChem

Similars
Article
PubMed
n/an/an/an/a 1.35E+3n/an/an/an/a



University of Vienna

Curated by ChEMBL


Assay Description
Inhibition of P-glycoprotein expressed in MDR CCRF vcr1000 cells by daunorubicin efflux assay

J Med Chem 50: 1698-702 (2007)


Article DOI: 10.1021/jm060604z
BindingDB Entry DOI: 10.7270/Q2SB46JC
More data for this
Ligand-Target Pair