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SMILES: CC(=O)c1cccc(OCC(O)CN2CCN(CC2)c2ccccc2C)c1

InChI Key: InChIKey=CHFFKXISONCMED-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50207930   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
ATP-dependent translocase ABCB1


(Homo sapiens (Human))		BDBM50207930
PNG
(1-(3-(2-hydroxy-3-(4-o-tolylpiperazin-1-yl)propoxy...)
Show SMILES CC(=O)c1cccc(OCC(O)CN2CCN(CC2)c2ccccc2C)c1
Show InChI InChI=1S/C22H28N2O3/c1-17-6-3-4-9-22(17)24-12-10-23(11-13-24)15-20(26)16-27-21-8-5-7-19(14-21)18(2)25/h3-9,14,20,26H,10-13,15-16H2,1-2H3
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Similars
Article
PubMed
n/an/an/an/a 537n/an/an/an/a



University of Vienna

Curated by ChEMBL


Assay Description
Inhibition of P-glycoprotein expressed in MDR CCRF vcr1000 cells by daunorubicin efflux assay

J Med Chem 50: 1698-702 (2007)


Article DOI: 10.1021/jm060604z
BindingDB Entry DOI: 10.7270/Q2SB46JC
More data for this
Ligand-Target Pair