BDBM50208203 CHEMBL3885093

SMILES: CN(C)CCSc1nc2ccccc2c2nc3ccccc3nc12

InChI Key: InChIKey=LYKPPCGHCCFWMF-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50208203   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Topoisomerase II alpha (HuTopoIIα) (Homo sapiens (Human))	BDBM50208203 (CHEMBL3885093) Show SMILES CN(C)CCSc1nc2ccccc2c2nc3ccccc3nc12 Show InChI InChI=1S/C19H18N4S/c1-23(2)11-12-24-19-18-17(13-7-3-4-8-14(13)22-19)20-15-9-5-6-10-16(15)21-18/h3-10H,11-12H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.78E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Bari"Aldo Moro" Curated by ChEMBL					Assay Description Inhibition of human DNA topoisomerase 2alpha-mediated decatenation of kinetoplast DNA after 60 mins by agarose gel electrophoresis				Eur J Med Chem 123: 704-717 (2016) Article DOI: 10.1016/j.ejmech.2016.07.063 BindingDB Entry DOI: 10.7270/Q2TQ63HJ
					More data for this Ligand-Target Pair