BDBM50208540 3-(6-morpholino-4-oxo-4H-pyran-2-yl)benzoic acid::CHEMBL222180

SMILES: OC(=O)c1cccc(c1)-c1cc(=O)cc(o1)N1CCOCC1

InChI Key: InChIKey=DIBMCWVULMJJDM-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50208540   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine-protein kinase ATM (Homo sapiens (Human))	BDBM50208540 (3-(6-morpholino-4-oxo-4H-pyran-2-yl)benzoic acid |...) Show SMILES OC(=O)c1cccc(c1)-c1cc(=O)cc(o1)N1CCOCC1 Show InChI InChI=1S/C16H15NO5/c18-13-9-14(11-2-1-3-12(8-11)16(19)20)22-15(10-13)17-4-6-21-7-5-17/h1-3,8-10H,4-7H2,(H,19,20)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Newcastle University Curated by ChEMBL					Assay Description Inhibition of ATM kinase				J Med Chem 50: 1958-72 (2007) Article DOI: 10.1021/jm061121y BindingDB Entry DOI: 10.7270/Q2FB52MW
					More data for this Ligand-Target Pair
DNA-dependent protein kinase catalytic subunit (Homo sapiens (Human))	BDBM50208540 (3-(6-morpholino-4-oxo-4H-pyran-2-yl)benzoic acid |...) Show SMILES OC(=O)c1cccc(c1)-c1cc(=O)cc(o1)N1CCOCC1 Show InChI InChI=1S/C16H15NO5/c18-13-9-14(11-2-1-3-12(8-11)16(19)20)22-15(10-13)17-4-6-21-7-5-17/h1-3,8-10H,4-7H2,(H,19,20)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Newcastle University Curated by ChEMBL					Assay Description Inhibition of DNA-PK in HeLa cell nuclear extracts				J Med Chem 50: 1958-72 (2007) Article DOI: 10.1021/jm061121y BindingDB Entry DOI: 10.7270/Q2FB52MW
					More data for this Ligand-Target Pair