BDBM50208608 CHEMBL3884305

SMILES: CCOc1ccc(cc1)-n1nnc(n1)-c1ccccc1NC(=O)c1ccc(OC)cc1

InChI Key: InChIKey=KWNWATIFBIPUJA-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50208608   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
ATP-binding cassette sub-family G member 2 (Homo sapiens (Human))	BDBM50208608 (CHEMBL3884305) Show SMILES CCOc1ccc(cc1)-n1nnc(n1)-c1ccccc1NC(=O)c1ccc(OC)cc1 Show InChI InChI=1S/C23H21N5O3/c1-3-31-19-14-10-17(11-15-19)28-26-22(25-27-28)20-6-4-5-7-21(20)24-23(29)16-8-12-18(30-2)13-9-16/h4-15H,3H2,1-2H3,(H,24,29)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	793	n/a	n/a	n/a	n/a	n/a	n/a
Rheinische Friedrich-Wilhelms-Universit£t Bonn Curated by ChEMBL					Assay Description Inhibition of recombinant human GFP-fused ABCG2 expressed in MDCK2 cells assessed as reduction in Hoechst 33342 efflux preincubated for 30 mins follo...				Eur J Med Chem 124: 881-895 (2016) Article DOI: 10.1016/j.ejmech.2016.09.010 BindingDB Entry DOI: 10.7270/Q28P62HT
					More data for this Ligand-Target Pair