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SMILES: COc1cc(Cn2c(CCc3ccccc3)nnc2[C@@H](Cc2c[nH]c3ccccc23)NC(=O)C(C)(C)N)cc(OC)c1

InChI Key: InChIKey=GBUPAIRVVQWJCN-GDLZYMKVSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50208698   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Growth hormone secretagogue receptor type 1


(Homo sapiens (Human))		BDBM50208698
PNG
((R)-N-(1-(4-(3,5-dimethoxybenzyl)-5-phenethyl-4H-1...)
Show SMILES COc1cc(Cn2c(CCc3ccccc3)nnc2[C@@H](Cc2c[nH]c3ccccc23)NC(=O)C(C)(C)N)cc(OC)c1
Show InChI InChI=1S/C33H38N6O3/c1-33(2,34)32(40)36-29(18-24-20-35-28-13-9-8-12-27(24)28)31-38-37-30(15-14-22-10-6-5-7-11-22)39(31)21-23-16-25(41-3)19-26(17-23)42-4/h5-13,16-17,19-20,29,35H,14-15,18,21,34H2,1-4H3,(H,36,40)/t29-/m1/s1
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Article
PubMed
n/an/a>1.00E+3n/an/an/an/an/an/a



CNRS-Universités Montpellier I et II

Curated by ChEMBL


Assay Description
Displacement of [125I-His9]ghrelin from human GHS1a receptor expressed in LLC PK1 cells

J Med Chem 50: 1939-57 (2007)


Article DOI: 10.1021/jm070024h
BindingDB Entry DOI: 10.7270/Q2251HW6
More data for this
Ligand-Target Pair