BDBM50208826 (+)-Pinoresinol::4-[(1S,3aR,4S,6aR)-4-(4-hydroxy-3-methoxyphenyl)tetrahydro-1H,3H-furo[3,4-c]furan-1-yl]-2-methoxyphenol::CHEMBL267963
SMILES: COc1cc(ccc1O)[C@@H]1OC[C@@H]2[C@H]1CO[C@H]2c1ccc(O)c(OC)c1
InChI Key: InChIKey=HGXBRUKMWQGOIE-NSMLZSOPSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Acidic alpha-glucosidase (Rattus norvegicus) | BDBM50208826 ((+)-Pinoresinol | 4-[(1S,3aR,4S,6aR)-4-(4-hydroxy-...) | PDB KEGG GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid PDB UniChem Similars | Article PubMed | 2.88E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Chulalongkorn University Curated by ChEMBL | Assay Description Competitive inhibition of rat intestinal maltase using maltose as substrate assessed as dissociation of enzyme-inhibitor complex at 0.1 to 1 mg/ml by... | Bioorg Med Chem Lett 22: 5215-7 (2012) Article DOI: 10.1016/j.bmcl.2012.06.068 BindingDB Entry DOI: 10.7270/Q28G8MR8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acidic alpha-glucosidase (Rattus norvegicus) | BDBM50208826 ((+)-Pinoresinol | 4-[(1S,3aR,4S,6aR)-4-(4-hydroxy-...) | PDB KEGG GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid PDB UniChem Similars | Article PubMed | 1.34E+6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Chulalongkorn University Curated by ChEMBL | Assay Description Non-competitive inhibition of rat intestinal maltase using maltose as substrate assessed as dissociation of enzyme-substrate-inhibitor complex at 0.1... | Bioorg Med Chem Lett 22: 5215-7 (2012) Article DOI: 10.1016/j.bmcl.2012.06.068 BindingDB Entry DOI: 10.7270/Q28G8MR8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acidic alpha-glucosidase (Rattus norvegicus) | BDBM50208826 ((+)-Pinoresinol | 4-[(1S,3aR,4S,6aR)-4-(4-hydroxy-...) | PDB KEGG GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | 3.43E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Chulalongkorn University Curated by ChEMBL | Assay Description Inhibition of rat intestinal maltase using maltose as substrate preincubated for 10 mins before substrate addition by glucose oxidase method | Bioorg Med Chem Lett 22: 5215-7 (2012) Article DOI: 10.1016/j.bmcl.2012.06.068 BindingDB Entry DOI: 10.7270/Q28G8MR8 | |||||||||||
More data for this Ligand-Target Pair |