BDBM50209175 CHEMBL396537::N,N-dimethyl-4-(5-nitro-1H-indol-3-yl)cyclohex-3-enamine
SMILES: CN(C)C1CCC(=CC1)c1c[nH]c2ccc(cc12)[N+]([O-])=O
InChI Key: InChIKey=OQPMHMPOPMZPGV-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Sodium-dependent serotonin transporter (Homo sapiens (Human)) | BDBM50209175 (CHEMBL396537 | N,N-dimethyl-4-(5-nitro-1H-indol-3-...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL | Assay Description Displacement of [3H]citalopram from human SERT expressed in HEK293 cells | Bioorg Med Chem Lett 17: 3099-104 (2007) Article DOI: 10.1016/j.bmcl.2007.03.040 BindingDB Entry DOI: 10.7270/Q2QN66F8 | |||||||||||
More data for this Ligand-Target Pair |