BDBM50209185 6-(5-chloro-2-hydroxyphenyl)-4-(2-chloro-5-(trifluoromethyl)phenyl)-2-oxo-1,2-dihydropyridine-3-carbonitrile::CHEMBL236620

SMILES: Oc1ccc(Cl)cc1-c1cc(-c2cc(ccc2Cl)C(F)(F)F)c(C#N)c(=O)[nH]1

InChI Key: InChIKey=HDKUBJYDFUJSOG-UHFFFAOYSA-N

Data: 1 Kd

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50209185   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Baculoviral IAP repeat-containing protein 5 (Homo sapiens (Human))	BDBM50209185 (6-(5-chloro-2-hydroxyphenyl)-4-(2-chloro-5-(triflu...) Show SMILES Oc1ccc(Cl)cc1-c1cc(-c2cc(ccc2Cl)C(F)(F)F)c(C#N)c(=O)[nH]1 Show InChI InChI=1S/C19H9Cl2F3N2O2/c20-10-2-4-17(27)13(6-10)16-7-11(14(8-25)18(28)26-16)12-5-9(19(22,23)24)1-3-15(12)21/h1-7,27H,(H,26,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	520	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding affinity to human survivin expressed in Escherichia coli BL21 cells after 30 mins				Bioorg Med Chem Lett 17: 3122-9 (2007) Article DOI: 10.1016/j.bmcl.2007.03.042 BindingDB Entry DOI: 10.7270/Q2M04534
					More data for this Ligand-Target Pair