BDBM50209192 6-(5-bromo-2-hydroxyphenyl)-4-(2,5-dimethylphenyl)-2-oxo-1,2-dihydropyridine-3-carbonitrile::CHEMBL236829

SMILES: Cc1ccc(C)c(c1)-c1cc([nH]c(=O)c1C#N)-c1cc(Br)ccc1O

InChI Key: InChIKey=XTBKZJJSYXEQSS-UHFFFAOYSA-N

Data: 1 Kd

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50209192   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Baculoviral IAP repeat-containing protein 5 (Homo sapiens (Human))	BDBM50209192 (6-(5-bromo-2-hydroxyphenyl)-4-(2,5-dimethylphenyl)...) Show SMILES Cc1ccc(C)c(c1)-c1cc([nH]c(=O)c1C#N)-c1cc(Br)ccc1O Show InChI InChI=1S/C20H15BrN2O2/c1-11-3-4-12(2)14(7-11)15-9-18(23-20(25)17(15)10-22)16-8-13(21)5-6-19(16)24/h3-9,24H,1-2H3,(H,23,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	1.17E+3	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding affinity to human survivin expressed in Escherichia coli BL21 cells after 30 mins				Bioorg Med Chem Lett 17: 3122-9 (2007) Article DOI: 10.1016/j.bmcl.2007.03.042 BindingDB Entry DOI: 10.7270/Q2M04534
					More data for this Ligand-Target Pair