BDBM50209543 (R)-2-[3-cyano-2-(2'-ethoxy-biphenyl-4-yl)-quinolin-4-ylamino]-propionic acid::CHEMBL248058

SMILES: CCOc1ccccc1-c1ccc(cc1)-c1nc2ccccc2c(N[C@H](C)C(O)=O)c1C#N

InChI Key: InChIKey=UXDIQNWZOHMMMV-QGZVFWFLSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50209543   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (Homo sapiens (Human))	BDBM50209543 ((R)-2-[3-cyano-2-(2'-ethoxy-biphenyl-4-yl)-quinoli...) Show SMILES CCOc1ccccc1-c1ccc(cc1)-c1nc2ccccc2c(N[C@H](C)C(O)=O)c1C#N Show InChI InChI=1S/C27H23N3O3/c1-3-33-24-11-7-5-8-20(24)18-12-14-19(15-13-18)25-22(16-28)26(29-17(2)27(31)32)21-9-4-6-10-23(21)30-25/h4-15,17H,3H2,1-2H3,(H,29,30)(H,31,32)/t17-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Bayer Pharmaceuticals Corporation Curated by ChEMBL					Assay Description Inhibition of human recombinant PDE10A transfected in insect Sf9 cells by scintillation proximity assay				Bioorg Med Chem Lett 17: 2869-73 (2007) Article DOI: 10.1016/j.bmcl.2007.02.061 BindingDB Entry DOI: 10.7270/Q2NS0TK0
					More data for this Ligand-Target Pair