BDBM50209679 CHEMBL234853::N-(3-(5-fluoro-1H-indol-3-yl)propyl)-2,3-dihydro-1H-pyrano[3,2-f]quinolin-2-amine

SMILES: Fc1ccc2[nH]cc(CCCNC3COc4ccc5ncccc5c4C3)c2c1

InChI Key: InChIKey=SUYYHJRBIBNGLJ-UHFFFAOYSA-N

Data: 6 KI  2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50209679   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium-dependent serotonin transporter (Rattus norvegicus (rat))	BDBM50209679 (CHEMBL234853 | N-(3-(5-fluoro-1H-indol-3-yl)propyl...) Show SMILES Fc1ccc2[nH]cc(CCCNC3COc4ccc5ncccc5c4C3)c2c1 |w:12.11| Show InChI InChI=1S/C23H22FN3O/c24-16-5-6-22-19(11-16)15(13-27-22)3-1-9-25-17-12-20-18-4-2-10-26-21(18)7-8-23(20)28-14-17/h2,4-8,10-11,13,17,25,27H,1,3,9,12,14H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]paroxetine from 5HT reuptake site of rat cortical 5HTT				Bioorg Med Chem Lett 17: 3117-21 (2007) Article DOI: 10.1016/j.bmcl.2007.03.049 BindingDB Entry DOI: 10.7270/Q2125SBH
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Rattus norvegicus (rat))	BDBM50209679 (CHEMBL234853 | N-(3-(5-fluoro-1H-indol-3-yl)propyl...) Show SMILES Fc1ccc2[nH]cc(CCCNC3COc4ccc5ncccc5c4C3)c2c1 |w:12.11| Show InChI InChI=1S/C23H22FN3O/c24-16-5-6-22-19(11-16)15(13-27-22)3-1-9-25-17-12-20-18-4-2-10-26-21(18)7-8-23(20)28-14-17/h2,4-8,10-11,13,17,25,27H,1,3,9,12,14H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]paroxetine from 5HT reuptake site of rat cortical 5HTT				Bioorg Med Chem Lett 17: 3117-21 (2007) Article DOI: 10.1016/j.bmcl.2007.03.049 BindingDB Entry DOI: 10.7270/Q2125SBH
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Rattus norvegicus (rat))	BDBM50209679 (CHEMBL234853 | N-(3-(5-fluoro-1H-indol-3-yl)propyl...) Show SMILES Fc1ccc2[nH]cc(CCCNC3COc4ccc5ncccc5c4C3)c2c1 |w:12.11| Show InChI InChI=1S/C23H22FN3O/c24-16-5-6-22-19(11-16)15(13-27-22)3-1-9-25-17-12-20-18-4-2-10-26-21(18)7-8-23(20)28-14-17/h2,4-8,10-11,13,17,25,27H,1,3,9,12,14H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]paroxetine from 5HT reuptake site of rat cortical 5HTT				Bioorg Med Chem Lett 17: 3117-21 (2007) Article DOI: 10.1016/j.bmcl.2007.03.049 BindingDB Entry DOI: 10.7270/Q2125SBH
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50209679 (CHEMBL234853 | N-(3-(5-fluoro-1H-indol-3-yl)propyl...) Show SMILES Fc1ccc2[nH]cc(CCCNC3COc4ccc5ncccc5c4C3)c2c1 |w:12.11| Show InChI InChI=1S/C23H22FN3O/c24-16-5-6-22-19(11-16)15(13-27-22)3-1-9-25-17-12-20-18-4-2-10-26-21(18)7-8-23(20)28-14-17/h2,4-8,10-11,13,17,25,27H,1,3,9,12,14H2	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	23.9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in CHO cells				Bioorg Med Chem Lett 17: 3117-21 (2007) Article DOI: 10.1016/j.bmcl.2007.03.049 BindingDB Entry DOI: 10.7270/Q2125SBH
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50209679 (CHEMBL234853 | N-(3-(5-fluoro-1H-indol-3-yl)propyl...) Show SMILES Fc1ccc2[nH]cc(CCCNC3COc4ccc5ncccc5c4C3)c2c1 |w:12.11| Show InChI InChI=1S/C23H22FN3O/c24-16-5-6-22-19(11-16)15(13-27-22)3-1-9-25-17-12-20-18-4-2-10-26-21(18)7-8-23(20)28-14-17/h2,4-8,10-11,13,17,25,27H,1,3,9,12,14H2	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	62.6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in CHO cells				Bioorg Med Chem Lett 17: 3117-21 (2007) Article DOI: 10.1016/j.bmcl.2007.03.049 BindingDB Entry DOI: 10.7270/Q2125SBH
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50209679 (CHEMBL234853 | N-(3-(5-fluoro-1H-indol-3-yl)propyl...) Show SMILES Fc1ccc2[nH]cc(CCCNC3COc4ccc5ncccc5c4C3)c2c1 |w:12.11| Show InChI InChI=1S/C23H22FN3O/c24-16-5-6-22-19(11-16)15(13-27-22)3-1-9-25-17-12-20-18-4-2-10-26-21(18)7-8-23(20)28-14-17/h2,4-8,10-11,13,17,25,27H,1,3,9,12,14H2	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	314	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in CHO cells				Bioorg Med Chem Lett 17: 3117-21 (2007) Article DOI: 10.1016/j.bmcl.2007.03.049 BindingDB Entry DOI: 10.7270/Q2125SBH
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50209679 (CHEMBL234853 | N-(3-(5-fluoro-1H-indol-3-yl)propyl...) Show SMILES Fc1ccc2[nH]cc(CCCNC3COc4ccc5ncccc5c4C3)c2c1 |w:12.11| Show InChI InChI=1S/C23H22FN3O/c24-16-5-6-22-19(11-16)15(13-27-22)3-1-9-25-17-12-20-18-4-2-10-26-21(18)7-8-23(20)28-14-17/h2,4-8,10-11,13,17,25,27H,1,3,9,12,14H2	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	182	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Agonist activity at human 5HT1A receptor expressed in CHO membrane assessed as stimulation of [35S]GTPgammaS binding				Bioorg Med Chem Lett 17: 3117-21 (2007) Article DOI: 10.1016/j.bmcl.2007.03.049 BindingDB Entry DOI: 10.7270/Q2125SBH
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50209679 (CHEMBL234853 | N-(3-(5-fluoro-1H-indol-3-yl)propyl...) Show SMILES Fc1ccc2[nH]cc(CCCNC3COc4ccc5ncccc5c4C3)c2c1 |w:12.11| Show InChI InChI=1S/C23H22FN3O/c24-16-5-6-22-19(11-16)15(13-27-22)3-1-9-25-17-12-20-18-4-2-10-26-21(18)7-8-23(20)28-14-17/h2,4-8,10-11,13,17,25,27H,1,3,9,12,14H2	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	116	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Agonist activity at human 5HT1A receptor expressed in CHO membrane assessed as stimulation of [35S]GTPgammaS binding				Bioorg Med Chem Lett 17: 3117-21 (2007) Article DOI: 10.1016/j.bmcl.2007.03.049 BindingDB Entry DOI: 10.7270/Q2125SBH
					More data for this Ligand-Target Pair