BDBM50209728 (R)-N-((R)-7-((tert-butylamino)methyl)chroman-4-yl)-3-(2-chlorophenylsulfonamido)-3-phenylpropanamide::CHEMBL375709

SMILES: CC(C)(C)NCc1ccc2[C@@H](CCOc2c1)NC(=O)C[C@@H](NS(=O)(=O)c1ccccc1Cl)c1ccccc1

InChI Key: InChIKey=LCPFUXDPAADHMG-JWQCQUIFSA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50209728   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
B1 bradykinin receptor (Homo sapiens (Human))	BDBM50209728 ((R)-N-((R)-7-((tert-butylamino)methyl)chroman-4-yl...) Show SMILES CC(C)(C)NCc1ccc2[C@@H](CCOc2c1)NC(=O)C[C@@H](NS(=O)(=O)c1ccccc1Cl)c1ccccc1 Show InChI InChI=1S/C29H34ClN3O4S/c1-29(2,3)31-19-20-13-14-22-24(15-16-37-26(22)17-20)32-28(34)18-25(21-9-5-4-6-10-21)33-38(35,36)27-12-8-7-11-23(27)30/h4-14,17,24-25,31,33H,15-16,18-19H2,1-3H3,(H,32,34)/t24-,25-/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	393	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Displacement of [3H]DAK from human bradykinin B1 receptor expressed in CHOD cells				J Med Chem 50: 2200-12 (2007) Article DOI: 10.1021/jm070055c BindingDB Entry DOI: 10.7270/Q2MS3SG2
					More data for this Ligand-Target Pair
B1 bradykinin receptor (Homo sapiens (Human))	BDBM50209728 ((R)-N-((R)-7-((tert-butylamino)methyl)chroman-4-yl...) Show SMILES CC(C)(C)NCc1ccc2[C@@H](CCOc2c1)NC(=O)C[C@@H](NS(=O)(=O)c1ccccc1Cl)c1ccccc1 Show InChI InChI=1S/C29H34ClN3O4S/c1-29(2,3)31-19-20-13-14-22-24(15-16-37-26(22)17-20)32-28(34)18-25(21-9-5-4-6-10-21)33-38(35,36)27-12-8-7-11-23(27)30/h4-14,17,24-25,31,33H,15-16,18-19H2,1-3H3,(H,32,34)/t24-,25-/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.03E+3	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Antagonist activity at human bradykinin B1 receptor expressed in CHOD cellsassessed as effect on DAK-induced calcium flux				J Med Chem 50: 2200-12 (2007) Article DOI: 10.1021/jm070055c BindingDB Entry DOI: 10.7270/Q2MS3SG2
					More data for this Ligand-Target Pair