null

SMILES: O=C(C[C@@H](NS(=O)(=O)c1ccc2ccccc2c1)c1ccccc1)N[C@@H]1CCOc2cc(CNC3CCCCC3)ccc12

InChI Key: InChIKey=VMHWKJXFQNGBJT-CZNDPXEESA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50209750   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
B1 bradykinin receptor (Homo sapiens (Human))	BDBM50209750 ((R)-N-((R)-7-((cyclohexylamino)methyl)chroman-4-yl...) Show SMILES O=C(C[C@@H](NS(=O)(=O)c1ccc2ccccc2c1)c1ccccc1)N[C@@H]1CCOc2cc(CNC3CCCCC3)ccc12 Show InChI InChI=1S/C35H39N3O4S/c39-35(37-32-19-20-42-34-21-25(15-18-31(32)34)24-36-29-13-5-2-6-14-29)23-33(27-10-3-1-4-11-27)38-43(40,41)30-17-16-26-9-7-8-12-28(26)22-30/h1,3-4,7-12,15-18,21-22,29,32-33,36,38H,2,5-6,13-14,19-20,23-24H2,(H,37,39)/t32-,33-/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	21.8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Displacement of [3H]DAK from human bradykinin B1 receptor expressed in CHOD cells				J Med Chem 50: 2200-12 (2007) Article DOI: 10.1021/jm070055c BindingDB Entry DOI: 10.7270/Q2MS3SG2
					More data for this Ligand-Target Pair
B1 bradykinin receptor (Homo sapiens (Human))	BDBM50209750 ((R)-N-((R)-7-((cyclohexylamino)methyl)chroman-4-yl...) Show SMILES O=C(C[C@@H](NS(=O)(=O)c1ccc2ccccc2c1)c1ccccc1)N[C@@H]1CCOc2cc(CNC3CCCCC3)ccc12 Show InChI InChI=1S/C35H39N3O4S/c39-35(37-32-19-20-42-34-21-25(15-18-31(32)34)24-36-29-13-5-2-6-14-29)23-33(27-10-3-1-4-11-27)38-43(40,41)30-17-16-26-9-7-8-12-28(26)22-30/h1,3-4,7-12,15-18,21-22,29,32-33,36,38H,2,5-6,13-14,19-20,23-24H2,(H,37,39)/t32-,33-/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	69.9	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Antagonist activity at human bradykinin B1 receptor expressed in CHOD cellsassessed as effect on DAK-induced calcium flux				J Med Chem 50: 2200-12 (2007) Article DOI: 10.1021/jm070055c BindingDB Entry DOI: 10.7270/Q2MS3SG2
					More data for this Ligand-Target Pair