Found 4 hits for monomerid = 50209867 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM50209867
(CHEMBL3884591)Show SMILES NS(=O)(=O)c1ccc(cc1)-c1nc2scc(-c3cccc(c3)[N+]([O-])=O)n2n1 Show InChI InChI=1S/C16H11N5O4S2/c17-27(24,25)13-6-4-10(5-7-13)15-18-16-20(19-15)14(9-26-16)11-2-1-3-12(8-11)21(22)23/h1-9H,(H2,17,24,25) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 13 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kurukshetra University
Curated by ChEMBL
| Assay Description Inhibition of recombinant human erythrocyte cytosolic carbonic anhydrase 2 by stopped-flow CO2 hydration assay |
Bioorg Med Chem 25: 1286-1293 (2017)
Article DOI: 10.1016/j.bmc.2016.12.047 BindingDB Entry DOI: 10.7270/Q2222WSR |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 1
(Homo sapiens (Human)) | BDBM50209867
(CHEMBL3884591)Show SMILES NS(=O)(=O)c1ccc(cc1)-c1nc2scc(-c3cccc(c3)[N+]([O-])=O)n2n1 Show InChI InChI=1S/C16H11N5O4S2/c17-27(24,25)13-6-4-10(5-7-13)15-18-16-20(19-15)14(9-26-16)11-2-1-3-12(8-11)21(22)23/h1-9H,(H2,17,24,25) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 64 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kurukshetra University
Curated by ChEMBL
| Assay Description Inhibition of recombinant human erythrocyte cytosolic carbonic anhydrase 1 by stopped-flow CO2 hydration assay |
Bioorg Med Chem 25: 1286-1293 (2017)
Article DOI: 10.1016/j.bmc.2016.12.047 BindingDB Entry DOI: 10.7270/Q2222WSR |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 9
(Homo sapiens (Human)) | BDBM50209867
(CHEMBL3884591)Show SMILES NS(=O)(=O)c1ccc(cc1)-c1nc2scc(-c3cccc(c3)[N+]([O-])=O)n2n1 Show InChI InChI=1S/C16H11N5O4S2/c17-27(24,25)13-6-4-10(5-7-13)15-18-16-20(19-15)14(9-26-16)11-2-1-3-12(8-11)21(22)23/h1-9H,(H2,17,24,25) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 203 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kurukshetra University
Curated by ChEMBL
| Assay Description Inhibition of recombinant human membrane bound carbonic anhydrase 9 by stopped-flow CO2 hydration assay |
Bioorg Med Chem 25: 1286-1293 (2017)
Article DOI: 10.1016/j.bmc.2016.12.047 BindingDB Entry DOI: 10.7270/Q2222WSR |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 12
(Homo sapiens (Human)) | BDBM50209867
(CHEMBL3884591)Show SMILES NS(=O)(=O)c1ccc(cc1)-c1nc2scc(-c3cccc(c3)[N+]([O-])=O)n2n1 Show InChI InChI=1S/C16H11N5O4S2/c17-27(24,25)13-6-4-10(5-7-13)15-18-16-20(19-15)14(9-26-16)11-2-1-3-12(8-11)21(22)23/h1-9H,(H2,17,24,25) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 362 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kurukshetra University
Curated by ChEMBL
| Assay Description Inhibition of recombinant human membrane bound carbonic anhydrase 12 by stopped-flow CO2 hydration assay |
Bioorg Med Chem 25: 1286-1293 (2017)
Article DOI: 10.1016/j.bmc.2016.12.047 BindingDB Entry DOI: 10.7270/Q2222WSR |
More data for this Ligand-Target Pair | |