Found 4 hits for monomerid = 50209874 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Carbonic anhydrase
(Homo sapiens (Human)) | BDBM50209874
(CHEMBL3884754)Show SMILES NS(=O)(=O)c1ccc(cc1)-c1nn2cc(nc2s1)-c1ccc(cc1)[N+]([O-])=O Show InChI InChI=1S/C16H11N5O4S2/c17-27(24,25)13-7-3-11(4-8-13)15-19-20-9-14(18-16(20)26-15)10-1-5-12(6-2-10)21(22)23/h1-9H,(H2,17,24,25) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 48 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kurukshetra University
Curated by ChEMBL
| Assay Description Inhibition of recombinant human membrane bound carbonic anhydrase 12 by stopped-flow CO2 hydration assay |
Bioorg Med Chem 25: 1286-1293 (2017)
Article DOI: 10.1016/j.bmc.2016.12.047 BindingDB Entry DOI: 10.7270/Q2222WSR |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 1
(Homo sapiens (Human)) | BDBM50209874
(CHEMBL3884754)Show SMILES NS(=O)(=O)c1ccc(cc1)-c1nn2cc(nc2s1)-c1ccc(cc1)[N+]([O-])=O Show InChI InChI=1S/C16H11N5O4S2/c17-27(24,25)13-7-3-11(4-8-13)15-19-20-9-14(18-16(20)26-15)10-1-5-12(6-2-10)21(22)23/h1-9H,(H2,17,24,25) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 287 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kurukshetra University
Curated by ChEMBL
| Assay Description Inhibition of recombinant human erythrocyte cytosolic carbonic anhydrase 1 by stopped-flow CO2 hydration assay |
Bioorg Med Chem 25: 1286-1293 (2017)
Article DOI: 10.1016/j.bmc.2016.12.047 BindingDB Entry DOI: 10.7270/Q2222WSR |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 9
(Homo sapiens (Human)) | BDBM50209874
(CHEMBL3884754)Show SMILES NS(=O)(=O)c1ccc(cc1)-c1nn2cc(nc2s1)-c1ccc(cc1)[N+]([O-])=O Show InChI InChI=1S/C16H11N5O4S2/c17-27(24,25)13-7-3-11(4-8-13)15-19-20-9-14(18-16(20)26-15)10-1-5-12(6-2-10)21(22)23/h1-9H,(H2,17,24,25) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 306 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kurukshetra University
Curated by ChEMBL
| Assay Description Inhibition of recombinant human membrane bound carbonic anhydrase 9 by stopped-flow CO2 hydration assay |
Bioorg Med Chem 25: 1286-1293 (2017)
Article DOI: 10.1016/j.bmc.2016.12.047 BindingDB Entry DOI: 10.7270/Q2222WSR |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM50209874
(CHEMBL3884754)Show SMILES NS(=O)(=O)c1ccc(cc1)-c1nn2cc(nc2s1)-c1ccc(cc1)[N+]([O-])=O Show InChI InChI=1S/C16H11N5O4S2/c17-27(24,25)13-7-3-11(4-8-13)15-19-20-9-14(18-16(20)26-15)10-1-5-12(6-2-10)21(22)23/h1-9H,(H2,17,24,25) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 369 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kurukshetra University
Curated by ChEMBL
| Assay Description Inhibition of recombinant human erythrocyte cytosolic carbonic anhydrase 2 by stopped-flow CO2 hydration assay |
Bioorg Med Chem 25: 1286-1293 (2017)
Article DOI: 10.1016/j.bmc.2016.12.047 BindingDB Entry DOI: 10.7270/Q2222WSR |
More data for this Ligand-Target Pair | |