BDBM50210027 3-(1-(4-chlorophenylsulfonyl)-1,2,3,4-tetrahydroquinolin-2-yl)propyl 1-benzylpiperidin-4-ylcarbamate::CHEMBL390889

SMILES: Clc1ccc(cc1)S(=O)(=O)N1C(CCCOC(=O)NC2CCN(Cc3ccccc3)CC2)CCc2ccccc12

InChI Key: InChIKey=ZHEYTIRGUSABKH-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50210027   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Beta amyloid A4 protein (Homo sapiens (Human))	BDBM50210027 (3-(1-(4-chlorophenylsulfonyl)-1,2,3,4-tetrahydroqu...) Show SMILES Clc1ccc(cc1)S(=O)(=O)N1C(CCCOC(=O)NC2CCN(Cc3ccccc3)CC2)CCc2ccccc12 Show InChI InChI=1S/C31H36ClN3O4S/c32-26-13-16-29(17-14-26)40(37,38)35-28(15-12-25-9-4-5-11-30(25)35)10-6-22-39-31(36)33-27-18-20-34(21-19-27)23-24-7-2-1-3-8-24/h1-5,7-9,11,13-14,16-17,27-28H,6,10,12,15,18-23H2,(H,33,36)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	190	n/a	n/a	n/a	n/a	n/a	n/a
Pharmacopeia Drug Discovery, Inc. Curated by ChEMBL					Assay Description Inhibition of gamma-secretase				Bioorg Med Chem Lett 17: 3010-3 (2007) Article DOI: 10.1016/j.bmcl.2007.03.055 BindingDB Entry DOI: 10.7270/Q2QJ7H0H
					More data for this Ligand-Target Pair