BDBM50210029 2-(1-(4-chlorophenylsulfonyl)-1,2,3,4-tetrahydroquinolin-2-yl)ethyl 1-benzylpiperidin-4-ylcarbamate::CHEMBL231647

SMILES: Clc1ccc(cc1)S(=O)(=O)N1C(CCOC(=O)NC2CCN(Cc3ccccc3)CC2)CCc2ccccc12

InChI Key: InChIKey=RSPHCRBPUSTDAH-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50210029   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Beta amyloid A4 protein (Homo sapiens (Human))	BDBM50210029 (2-(1-(4-chlorophenylsulfonyl)-1,2,3,4-tetrahydroqu...) Show SMILES Clc1ccc(cc1)S(=O)(=O)N1C(CCOC(=O)NC2CCN(Cc3ccccc3)CC2)CCc2ccccc12 Show InChI InChI=1S/C30H34ClN3O4S/c31-25-11-14-28(15-12-25)39(36,37)34-27(13-10-24-8-4-5-9-29(24)34)18-21-38-30(35)32-26-16-19-33(20-17-26)22-23-6-2-1-3-7-23/h1-9,11-12,14-15,26-27H,10,13,16-22H2,(H,32,35)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	900	n/a	n/a	n/a	n/a	n/a	n/a
Pharmacopeia Drug Discovery, Inc. Curated by ChEMBL					Assay Description Inhibition of gamma-secretase				Bioorg Med Chem Lett 17: 3010-3 (2007) Article DOI: 10.1016/j.bmcl.2007.03.055 BindingDB Entry DOI: 10.7270/Q2QJ7H0H
					More data for this Ligand-Target Pair