BDBM50210206 4-(2-(aminomethyl)phenyl)-1-(dio-tolylmethyl)piperidin-4-ol::CHEMBL400035

SMILES: Cc1ccccc1C(N1CCC(O)(CC1)c1ccccc1CN)c1ccccc1C

InChI Key: InChIKey=ZUCAHKWKUIULAI-UHFFFAOYSA-N

Data: 4 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50210206   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nociceptin receptor (Homo sapiens (Human))	BDBM50210206 (4-(2-(aminomethyl)phenyl)-1-(dio-tolylmethyl)piper...) Show SMILES Cc1ccccc1C(N1CCC(O)(CC1)c1ccccc1CN)c1ccccc1C Show InChI InChI=1S/C27H32N2O/c1-20-9-3-6-12-23(20)26(24-13-7-4-10-21(24)2)29-17-15-27(30,16-18-29)25-14-8-5-11-22(25)19-28/h3-14,26,30H,15-19,28H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Displacement of [125I][Tyr14]nociceptin FQ from human NOP receptor expressed in CHO cell membrane				Bioorg Med Chem Lett 17: 3028-33 (2007) Article DOI: 10.1016/j.bmcl.2007.03.062 BindingDB Entry DOI: 10.7270/Q2Z31ZBS
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50210206 (4-(2-(aminomethyl)phenyl)-1-(dio-tolylmethyl)piper...) Show SMILES Cc1ccccc1C(N1CCC(O)(CC1)c1ccccc1CN)c1ccccc1C Show InChI InChI=1S/C27H32N2O/c1-20-9-3-6-12-23(20)26(24-13-7-4-10-21(24)2)29-17-15-27(30,16-18-29)25-14-8-5-11-22(25)19-28/h3-14,26,30H,15-19,28H2,1-2H3	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	190	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]diprenorphine from human MOP receptor expressed in CHO cell membrane				Bioorg Med Chem Lett 17: 3028-33 (2007) Article DOI: 10.1016/j.bmcl.2007.03.062 BindingDB Entry DOI: 10.7270/Q2Z31ZBS
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50210206 (4-(2-(aminomethyl)phenyl)-1-(dio-tolylmethyl)piper...) Show SMILES Cc1ccccc1C(N1CCC(O)(CC1)c1ccccc1CN)c1ccccc1C Show InChI InChI=1S/C27H32N2O/c1-20-9-3-6-12-23(20)26(24-13-7-4-10-21(24)2)29-17-15-27(30,16-18-29)25-14-8-5-11-22(25)19-28/h3-14,26,30H,15-19,28H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	450	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]diprenorphine from human KOP receptor expressed in CHO cell membrane				Bioorg Med Chem Lett 17: 3028-33 (2007) Article DOI: 10.1016/j.bmcl.2007.03.062 BindingDB Entry DOI: 10.7270/Q2Z31ZBS
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50210206 (4-(2-(aminomethyl)phenyl)-1-(dio-tolylmethyl)piper...) Show SMILES Cc1ccccc1C(N1CCC(O)(CC1)c1ccccc1CN)c1ccccc1C Show InChI InChI=1S/C27H32N2O/c1-20-9-3-6-12-23(20)26(24-13-7-4-10-21(24)2)29-17-15-27(30,16-18-29)25-14-8-5-11-22(25)19-28/h3-14,26,30H,15-19,28H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	8.44E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]diprenorphine from human DOP receptor expressed in CHO cell membrane				Bioorg Med Chem Lett 17: 3028-33 (2007) Article DOI: 10.1016/j.bmcl.2007.03.062 BindingDB Entry DOI: 10.7270/Q2Z31ZBS
					More data for this Ligand-Target Pair