BDBM50210389 1-(bis(2-methoxyphenyl)methyl)-4-phenylpiperidin-4-ol::CHEMBL228964

SMILES: COc1ccccc1C(N1CCC(O)(CC1)c1ccccc1)c1ccccc1OC

InChI Key: InChIKey=MEIKCNSXEAPYGM-UHFFFAOYSA-N

Data: 4 KI  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50210389   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nociceptin receptor (Homo sapiens (Human))	BDBM50210389 (1-(bis(2-methoxyphenyl)methyl)-4-phenylpiperidin-4...) Show SMILES COc1ccccc1C(N1CCC(O)(CC1)c1ccccc1)c1ccccc1OC Show InChI InChI=1S/C26H29NO3/c1-29-23-14-8-6-12-21(23)25(22-13-7-9-15-24(22)30-2)27-18-16-26(28,17-19-27)20-10-4-3-5-11-20/h3-15,25,28H,16-19H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Agonist activity at human NOP receptor expressed in CHO cells assessed as stimulation of [35S]GTP-gamma-S binding				Bioorg Med Chem Lett 17: 3023-7 (2007) Article DOI: 10.1016/j.bmcl.2007.03.061 BindingDB Entry DOI: 10.7270/Q24B3242
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50210389 (1-(bis(2-methoxyphenyl)methyl)-4-phenylpiperidin-4...) Show SMILES COc1ccccc1C(N1CCC(O)(CC1)c1ccccc1)c1ccccc1OC Show InChI InChI=1S/C26H29NO3/c1-29-23-14-8-6-12-21(23)25(22-13-7-9-15-24(22)30-2)27-18-16-26(28,17-19-27)20-10-4-3-5-11-20/h3-15,25,28H,16-19H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	306	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]diprenorphine from human KOP receptor expressed in CHO cell membranes				Bioorg Med Chem Lett 17: 3023-7 (2007) Article DOI: 10.1016/j.bmcl.2007.03.061 BindingDB Entry DOI: 10.7270/Q24B3242
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50210389 (1-(bis(2-methoxyphenyl)methyl)-4-phenylpiperidin-4...) Show SMILES COc1ccccc1C(N1CCC(O)(CC1)c1ccccc1)c1ccccc1OC Show InChI InChI=1S/C26H29NO3/c1-29-23-14-8-6-12-21(23)25(22-13-7-9-15-24(22)30-2)27-18-16-26(28,17-19-27)20-10-4-3-5-11-20/h3-15,25,28H,16-19H2,1-2H3	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	843	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]diprenorphine from human MOP receptor expressed in CHO cell membranes				Bioorg Med Chem Lett 17: 3023-7 (2007) Article DOI: 10.1016/j.bmcl.2007.03.061 BindingDB Entry DOI: 10.7270/Q24B3242
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50210389 (1-(bis(2-methoxyphenyl)methyl)-4-phenylpiperidin-4...) Show SMILES COc1ccccc1C(N1CCC(O)(CC1)c1ccccc1)c1ccccc1OC Show InChI InChI=1S/C26H29NO3/c1-29-23-14-8-6-12-21(23)25(22-13-7-9-15-24(22)30-2)27-18-16-26(28,17-19-27)20-10-4-3-5-11-20/h3-15,25,28H,16-19H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.82E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]diprenorphine from human DOP receptor expressed in CHO cell membranes				Bioorg Med Chem Lett 17: 3023-7 (2007) Article DOI: 10.1016/j.bmcl.2007.03.061 BindingDB Entry DOI: 10.7270/Q24B3242
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50210389 (1-(bis(2-methoxyphenyl)methyl)-4-phenylpiperidin-4...) Show SMILES COc1ccccc1C(N1CCC(O)(CC1)c1ccccc1)c1ccccc1OC Show InChI InChI=1S/C26H29NO3/c1-29-23-14-8-6-12-21(23)25(22-13-7-9-15-24(22)30-2)27-18-16-26(28,17-19-27)20-10-4-3-5-11-20/h3-15,25,28H,16-19H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	117	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Agonist activity at human NOP receptor expressed in CHO cells assessed as stimulation of [35S]GTP-gamma-S binding				Bioorg Med Chem Lett 17: 3023-7 (2007) Article DOI: 10.1016/j.bmcl.2007.03.061 BindingDB Entry DOI: 10.7270/Q24B3242
					More data for this Ligand-Target Pair