BDBM50210408 1-(2-methoxy-1-phenylethyl)-4-phenylpiperidin-4-ol::CHEMBL228686

SMILES: COCC(N1CCC(O)(CC1)c1ccccc1)c1ccccc1

InChI Key: InChIKey=QGTSAVPZRGXSBO-UHFFFAOYSA-N

Data: 4 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50210408   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nociceptin receptor (Homo sapiens (Human))	BDBM50210408 (1-(2-methoxy-1-phenylethyl)-4-phenylpiperidin-4-ol...) Show SMILES COCC(N1CCC(O)(CC1)c1ccccc1)c1ccccc1 |w:3.2| Show InChI InChI=1S/C20H25NO2/c1-23-16-19(17-8-4-2-5-9-17)21-14-12-20(22,13-15-21)18-10-6-3-7-11-18/h2-11,19,22H,12-16H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	295	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Agonist activity at human NOP receptor expressed in CHO cells assessed as stimulation of [35S]GTP-gamma-S binding				Bioorg Med Chem Lett 17: 3023-7 (2007) Article DOI: 10.1016/j.bmcl.2007.03.061 BindingDB Entry DOI: 10.7270/Q24B3242
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50210408 (1-(2-methoxy-1-phenylethyl)-4-phenylpiperidin-4-ol...) Show SMILES COCC(N1CCC(O)(CC1)c1ccccc1)c1ccccc1 |w:3.2| Show InChI InChI=1S/C20H25NO2/c1-23-16-19(17-8-4-2-5-9-17)21-14-12-20(22,13-15-21)18-10-6-3-7-11-18/h2-11,19,22H,12-16H2,1H3	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	780	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]diprenorphine from human MOP receptor expressed in CHO cell membranes				Bioorg Med Chem Lett 17: 3023-7 (2007) Article DOI: 10.1016/j.bmcl.2007.03.061 BindingDB Entry DOI: 10.7270/Q24B3242
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50210408 (1-(2-methoxy-1-phenylethyl)-4-phenylpiperidin-4-ol...) Show SMILES COCC(N1CCC(O)(CC1)c1ccccc1)c1ccccc1 |w:3.2| Show InChI InChI=1S/C20H25NO2/c1-23-16-19(17-8-4-2-5-9-17)21-14-12-20(22,13-15-21)18-10-6-3-7-11-18/h2-11,19,22H,12-16H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.77E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]diprenorphine from human KOP receptor expressed in CHO cell membranes				Bioorg Med Chem Lett 17: 3023-7 (2007) Article DOI: 10.1016/j.bmcl.2007.03.061 BindingDB Entry DOI: 10.7270/Q24B3242
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50210408 (1-(2-methoxy-1-phenylethyl)-4-phenylpiperidin-4-ol...) Show SMILES COCC(N1CCC(O)(CC1)c1ccccc1)c1ccccc1 |w:3.2| Show InChI InChI=1S/C20H25NO2/c1-23-16-19(17-8-4-2-5-9-17)21-14-12-20(22,13-15-21)18-10-6-3-7-11-18/h2-11,19,22H,12-16H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.30E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]diprenorphine from human DOP receptor expressed in CHO cell membranes				Bioorg Med Chem Lett 17: 3023-7 (2007) Article DOI: 10.1016/j.bmcl.2007.03.061 BindingDB Entry DOI: 10.7270/Q24B3242
					More data for this Ligand-Target Pair