BDBM50210502 CHEMBL249937::cyclopropanecarboxylic acid {4-[7-dimethylaminomethyl-2-(4-fluorophenyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-2-yl}amide

SMILES: CN(C)Cc1ccn2c(c(nc2c1)-c1ccc(F)cc1)-c1ccnc(NC(=O)C2CC2)n1

InChI Key: InChIKey=QNIFAASGNLDODC-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50210502   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cGMP-dependent protein kinase (Eimeria tenella)	BDBM50210502 (CHEMBL249937 | cyclopropanecarboxylic acid {4-[7-d...) Show SMILES CN(C)Cc1ccn2c(c(nc2c1)-c1ccc(F)cc1)-c1ccnc(NC(=O)C2CC2)n1 Show InChI InChI=1S/C24H23FN6O/c1-30(2)14-15-10-12-31-20(13-15)28-21(16-5-7-18(25)8-6-16)22(31)19-9-11-26-24(27-19)29-23(32)17-3-4-17/h5-13,17H,3-4,14H2,1-2H3,(H,26,27,29,32)	UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.420	n/a	n/a	n/a	n/a	n/a	n/a
SCYNEXIS, Inc. Curated by ChEMBL					Assay Description Inhibition of Eimeria tenella cGMP-dependent protein kinase by Ten_K assay				Eur J Med Chem 42: 1334-57 (2007) Article DOI: 10.1016/j.ejmech.2007.02.006 BindingDB Entry DOI: 10.7270/Q2SB45FM
					More data for this Ligand-Target Pair