BDBM50210530 (S)-2-(2,6-Dioxo-3-(3,4,5-trimethoxybenzamido)piperidin-1-yl)acetic acid::CHEMBL246178

SMILES: COc1cc(cc(OC)c1OC)C(=O)N[C@H]1CCC(=O)N(CC(O)=O)C1=O

InChI Key: InChIKey=BIVVTMYKPQBBMU-JTQLQIEISA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50210530   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Aminopeptidase N (Sus scrofa (Pig))	BDBM50210530 ((S)-2-(2,6-Dioxo-3-(3,4,5-trimethoxybenzamido)pipe...) Show SMILES COc1cc(cc(OC)c1OC)C(=O)N[C@H]1CCC(=O)N(CC(O)=O)C1=O Show InChI InChI=1S/C17H20N2O8/c1-25-11-6-9(7-12(26-2)15(11)27-3)16(23)18-10-4-5-13(20)19(17(10)24)8-14(21)22/h6-7,10H,4-5,8H2,1-3H3,(H,18,23)(H,21,22)/t10-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.98E+4	n/a	n/a	n/a	n/a	n/a	n/a
Shandong University Curated by ChEMBL					Assay Description Inhibition of pig kidney microsomal aminopeptidase assessed as liberation of p-nitroanilide				Bioorg Med Chem Lett 17: 2935-8 (2007) Article DOI: 10.1016/j.bmcl.2006.12.095 BindingDB Entry DOI: 10.7270/Q2HT2P11
					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM50210530 ((S)-2-(2,6-Dioxo-3-(3,4,5-trimethoxybenzamido)pipe...) Show SMILES COc1cc(cc(OC)c1OC)C(=O)N[C@H]1CCC(=O)N(CC(O)=O)C1=O Show InChI InChI=1S/C17H20N2O8/c1-25-11-6-9(7-12(26-2)15(11)27-3)16(23)18-10-4-5-13(20)19(17(10)24)8-14(21)22/h6-7,10H,4-5,8H2,1-3H3,(H,18,23)(H,21,22)/t10-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Shandong University Curated by ChEMBL					Assay Description Inhibition of MMP2 after 30 mins				Bioorg Med Chem Lett 17: 2935-8 (2007) Article DOI: 10.1016/j.bmcl.2006.12.095 BindingDB Entry DOI: 10.7270/Q2HT2P11
					More data for this Ligand-Target Pair
Aminopeptidase N (Sus scrofa (Pig))	BDBM50210530 ((S)-2-(2,6-Dioxo-3-(3,4,5-trimethoxybenzamido)pipe...) Show SMILES COc1cc(cc(OC)c1OC)C(=O)N[C@H]1CCC(=O)N(CC(O)=O)C1=O Show InChI InChI=1S/C17H20N2O8/c1-25-11-6-9(7-12(26-2)15(11)27-3)16(23)18-10-4-5-13(20)19(17(10)24)8-14(21)22/h6-7,10H,4-5,8H2,1-3H3,(H,18,23)(H,21,22)/t10-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.98E+4	n/a	n/a	n/a	n/a	n/a	n/a
Shandong University Curated by ChEMBL					Assay Description Inhibition of pig kidney microsomes aminopeptidase N preincubated for 30 mins				Eur J Med Chem 44: 4819-25 (2009) Article DOI: 10.1016/j.ejmech.2009.07.022 BindingDB Entry DOI: 10.7270/Q2251J73
					More data for this Ligand-Target Pair