BDBM50210589 CHEMBL247130::N-(4-chlorobenzyl)-2-(morpholinomethyl)-4-oxo-4,7-dihydrothieno[2,3-b]pyridine-5-carboxamide

SMILES: Oc1c(cnc2sc(CN3CCOCC3)cc12)C(=O)NCc1ccc(Cl)cc1

InChI Key: InChIKey=CFKIMGPJOCQJHM-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50210589   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
DNA polymerase (Human cytomegalovirus (HCMV strain AD169) )	BDBM50210589 (CHEMBL247130 | N-(4-chlorobenzyl)-2-(morpholinomet...) Show SMILES Oc1c(cnc2sc(CN3CCOCC3)cc12)C(=O)NCc1ccc(Cl)cc1 Show InChI InChI=1S/C20H20ClN3O3S/c21-14-3-1-13(2-4-14)10-22-19(26)17-11-23-20-16(18(17)25)9-15(28-20)12-24-5-7-27-8-6-24/h1-4,9,11H,5-8,10,12H2,(H,22,26)(H,23,25)	UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of HCMV DNA polymerase by scintillation proximity assay				Bioorg Med Chem Lett 17: 3349-53 (2007) Article DOI: 10.1016/j.bmcl.2007.03.102 BindingDB Entry DOI: 10.7270/Q2HX1DHN
					More data for this Ligand-Target Pair