BDBM50210651 (R)-ethyl 7-(3-amino-4-(2,5-difluorophenyl)butanoyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine-3-carboxylate::CHEMBL389600

SMILES: CCOC(=O)c1nnc2CN(CCn12)C(=O)C[C@H](N)Cc1cc(F)ccc1F

InChI Key: InChIKey=DHWNCDYJQCLUTQ-CYBMUJFWSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50210651   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dipeptidyl peptidase VIII (Homo sapiens (Human))	BDBM50210651 ((R)-ethyl 7-(3-amino-4-(2,5-difluorophenyl)butanoy...) Show SMILES CCOC(=O)c1nnc2CN(CCn12)C(=O)C[C@H](N)Cc1cc(F)ccc1F Show InChI InChI=1S/C18H21F2N5O3/c1-2-28-18(27)17-23-22-15-10-24(5-6-25(15)17)16(26)9-13(21)8-11-7-12(19)3-4-14(11)20/h3-4,7,13H,2,5-6,8-10,21H2,1H3/t13-/m1/s1	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of DPP8 activity				Bioorg Med Chem Lett 17: 3373-7 (2007) Article DOI: 10.1016/j.bmcl.2007.03.098 BindingDB Entry DOI: 10.7270/Q2W37W04
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM50210651 ((R)-ethyl 7-(3-amino-4-(2,5-difluorophenyl)butanoy...) Show SMILES CCOC(=O)c1nnc2CN(CCn12)C(=O)C[C@H](N)Cc1cc(F)ccc1F Show InChI InChI=1S/C18H21F2N5O3/c1-2-28-18(27)17-23-22-15-10-24(5-6-25(15)17)16(26)9-13(21)8-11-7-12(19)3-4-14(11)20/h3-4,7,13H,2,5-6,8-10,21H2,1H3/t13-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	190	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of DPP4 activity				Bioorg Med Chem Lett 17: 3373-7 (2007) Article DOI: 10.1016/j.bmcl.2007.03.098 BindingDB Entry DOI: 10.7270/Q2W37W04
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 9 (Homo sapiens (Human))	BDBM50210651 ((R)-ethyl 7-(3-amino-4-(2,5-difluorophenyl)butanoy...) Show SMILES CCOC(=O)c1nnc2CN(CCn12)C(=O)C[C@H](N)Cc1cc(F)ccc1F Show InChI InChI=1S/C18H21F2N5O3/c1-2-28-18(27)17-23-22-15-10-24(5-6-25(15)17)16(26)9-13(21)8-11-7-12(19)3-4-14(11)20/h3-4,7,13H,2,5-6,8-10,21H2,1H3/t13-/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>7.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of DPP9 activity				Bioorg Med Chem Lett 17: 3373-7 (2007) Article DOI: 10.1016/j.bmcl.2007.03.098 BindingDB Entry DOI: 10.7270/Q2W37W04
					More data for this Ligand-Target Pair