BDBM50210663 (R)-3-amino-4-(2-fluorophenyl)-1-(3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)butan-1-one::CHEMBL388475

SMILES: N[C@@H](CC(=O)N1CCn2c(C1)nnc2C(F)(F)F)Cc1ccccc1F

InChI Key: InChIKey=ZLZZDLNHNLSAJF-LLVKDONJSA-N

Data: 5 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50210663   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dipeptidyl peptidase 9 (Homo sapiens (Human))	BDBM50210663 ((R)-3-amino-4-(2-fluorophenyl)-1-(3-(trifluorometh...) Show SMILES N[C@@H](CC(=O)N1CCn2c(C1)nnc2C(F)(F)F)Cc1ccccc1F |r| Show InChI InChI=1S/C16H17F4N5O/c17-12-4-2-1-3-10(12)7-11(21)8-14(26)24-5-6-25-13(9-24)22-23-15(25)16(18,19)20/h1-4,11H,5-9,21H2/t11-/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of DPP9 activity				Bioorg Med Chem Lett 17: 3373-7 (2007) Article DOI: 10.1016/j.bmcl.2007.03.098 BindingDB Entry DOI: 10.7270/Q2W37W04
					More data for this Ligand-Target Pair
Dipeptidyl peptidase VIII (Homo sapiens (Human))	BDBM50210663 ((R)-3-amino-4-(2-fluorophenyl)-1-(3-(trifluorometh...) Show SMILES N[C@@H](CC(=O)N1CCn2c(C1)nnc2C(F)(F)F)Cc1ccccc1F |r| Show InChI InChI=1S/C16H17F4N5O/c17-12-4-2-1-3-10(12)7-11(21)8-14(26)24-5-6-25-13(9-24)22-23-15(25)16(18,19)20/h1-4,11H,5-9,21H2/t11-/m1/s1	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of DPP8 activity				Bioorg Med Chem Lett 17: 3373-7 (2007) Article DOI: 10.1016/j.bmcl.2007.03.098 BindingDB Entry DOI: 10.7270/Q2W37W04
					More data for this Ligand-Target Pair
Dipeptidyl peptidase VIII (Homo sapiens (Human))	BDBM50210663 ((R)-3-amino-4-(2-fluorophenyl)-1-(3-(trifluorometh...) Show SMILES N[C@@H](CC(=O)N1CCn2c(C1)nnc2C(F)(F)F)Cc1ccccc1F |r| Show InChI InChI=1S/C16H17F4N5O/c17-12-4-2-1-3-10(12)7-11(21)8-14(26)24-5-6-25-13(9-24)22-23-15(25)16(18,19)20/h1-4,11H,5-9,21H2/t11-/m1/s1	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of DPP8 (unknown origin)				Bioorg Med Chem Lett 18: 3706-10 (2008) Article DOI: 10.1016/j.bmcl.2008.05.061 BindingDB Entry DOI: 10.7270/Q24T6J6Q
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM50210663 ((R)-3-amino-4-(2-fluorophenyl)-1-(3-(trifluorometh...) Show SMILES N[C@@H](CC(=O)N1CCn2c(C1)nnc2C(F)(F)F)Cc1ccccc1F |r| Show InChI InChI=1S/C16H17F4N5O/c17-12-4-2-1-3-10(12)7-11(21)8-14(26)24-5-6-25-13(9-24)22-23-15(25)16(18,19)20/h1-4,11H,5-9,21H2/t11-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	98	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of DPP4 (unknown origin)				Bioorg Med Chem Lett 18: 3706-10 (2008) Article DOI: 10.1016/j.bmcl.2008.05.061 BindingDB Entry DOI: 10.7270/Q24T6J6Q
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM50210663 ((R)-3-amino-4-(2-fluorophenyl)-1-(3-(trifluorometh...) Show SMILES N[C@@H](CC(=O)N1CCn2c(C1)nnc2C(F)(F)F)Cc1ccccc1F |r| Show InChI InChI=1S/C16H17F4N5O/c17-12-4-2-1-3-10(12)7-11(21)8-14(26)24-5-6-25-13(9-24)22-23-15(25)16(18,19)20/h1-4,11H,5-9,21H2/t11-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	98	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of DPP4 activity				Bioorg Med Chem Lett 17: 3373-7 (2007) Article DOI: 10.1016/j.bmcl.2007.03.098 BindingDB Entry DOI: 10.7270/Q2W37W04
					More data for this Ligand-Target Pair