BDBM50210667 (R)-3-amino-1-(3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)-4-(4-(trifluoromethyl)phenyl)butan-1-one::CHEMBL245181

SMILES: N[C@@H](CC(=O)N1CCn2c(C1)nnc2C(F)(F)F)Cc1ccc(cc1)C(F)(F)F

InChI Key: InChIKey=PBIJFKVXMQJXSJ-GFCCVEGCSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50210667   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dipeptidyl peptidase VIII (Homo sapiens (Human))	BDBM50210667 ((R)-3-amino-1-(3-(trifluoromethyl)-5,6-dihydro-[1,...) Show SMILES N[C@@H](CC(=O)N1CCn2c(C1)nnc2C(F)(F)F)Cc1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C17H17F6N5O/c18-16(19,20)11-3-1-10(2-4-11)7-12(24)8-14(29)27-5-6-28-13(9-27)25-26-15(28)17(21,22)23/h1-4,12H,5-9,24H2/t12-/m1/s1	PDB KEGG GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of DPP8 activity				Bioorg Med Chem Lett 17: 3373-7 (2007) Article DOI: 10.1016/j.bmcl.2007.03.098 BindingDB Entry DOI: 10.7270/Q2W37W04
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 9 (Homo sapiens (Human))	BDBM50210667 ((R)-3-amino-1-(3-(trifluoromethyl)-5,6-dihydro-[1,...) Show SMILES N[C@@H](CC(=O)N1CCn2c(C1)nnc2C(F)(F)F)Cc1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C17H17F6N5O/c18-16(19,20)11-3-1-10(2-4-11)7-12(24)8-14(29)27-5-6-28-13(9-27)25-26-15(28)17(21,22)23/h1-4,12H,5-9,24H2/t12-/m1/s1	PDB KEGG GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of DPP9 activity				Bioorg Med Chem Lett 17: 3373-7 (2007) Article DOI: 10.1016/j.bmcl.2007.03.098 BindingDB Entry DOI: 10.7270/Q2W37W04
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM50210667 ((R)-3-amino-1-(3-(trifluoromethyl)-5,6-dihydro-[1,...) Show SMILES N[C@@H](CC(=O)N1CCn2c(C1)nnc2C(F)(F)F)Cc1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C17H17F6N5O/c18-16(19,20)11-3-1-10(2-4-11)7-12(24)8-14(29)27-5-6-28-13(9-27)25-26-15(28)17(21,22)23/h1-4,12H,5-9,24H2/t12-/m1/s1	PDB MMDB Reactome pathway KEGG B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	511	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of DPP4 activity				Bioorg Med Chem Lett 17: 3373-7 (2007) Article DOI: 10.1016/j.bmcl.2007.03.098 BindingDB Entry DOI: 10.7270/Q2W37W04
					More data for this Ligand-Target Pair