BDBM50210668 (3R)-3-amino-4-(2,5-difluorophenyl)-1-(3-(2,4-difluorophenyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)butan-1-one::CHEMBL389599

SMILES: N[C@@H](CC(=O)N1CCn2c(C1)nnc2-c1ccc(F)cc1F)Cc1cc(F)ccc1F

InChI Key: InChIKey=CPKSIOFLZDEMJS-OAHLLOKOSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50210668   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM50210668 ((3R)-3-amino-4-(2,5-difluorophenyl)-1-(3-(2,4-difl...) Show SMILES N[C@@H](CC(=O)N1CCn2c(C1)nnc2-c1ccc(F)cc1F)Cc1cc(F)ccc1F Show InChI InChI=1S/C21H19F4N5O/c22-13-2-4-17(24)12(7-13)8-15(26)10-20(31)29-5-6-30-19(11-29)27-28-21(30)16-3-1-14(23)9-18(16)25/h1-4,7,9,15H,5-6,8,10-11,26H2/t15-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of DPP4 activity				Bioorg Med Chem Lett 17: 3373-7 (2007) Article DOI: 10.1016/j.bmcl.2007.03.098 BindingDB Entry DOI: 10.7270/Q2W37W04
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 9 (Homo sapiens (Human))	BDBM50210668 ((3R)-3-amino-4-(2,5-difluorophenyl)-1-(3-(2,4-difl...) Show SMILES N[C@@H](CC(=O)N1CCn2c(C1)nnc2-c1ccc(F)cc1F)Cc1cc(F)ccc1F Show InChI InChI=1S/C21H19F4N5O/c22-13-2-4-17(24)12(7-13)8-15(26)10-20(31)29-5-6-30-19(11-29)27-28-21(30)16-3-1-14(23)9-18(16)25/h1-4,7,9,15H,5-6,8,10-11,26H2/t15-/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of DPP9 activity				Bioorg Med Chem Lett 17: 3373-7 (2007) Article DOI: 10.1016/j.bmcl.2007.03.098 BindingDB Entry DOI: 10.7270/Q2W37W04
					More data for this Ligand-Target Pair
Dipeptidyl peptidase VIII (Homo sapiens (Human))	BDBM50210668 ((3R)-3-amino-4-(2,5-difluorophenyl)-1-(3-(2,4-difl...) Show SMILES N[C@@H](CC(=O)N1CCn2c(C1)nnc2-c1ccc(F)cc1F)Cc1cc(F)ccc1F Show InChI InChI=1S/C21H19F4N5O/c22-13-2-4-17(24)12(7-13)8-15(26)10-20(31)29-5-6-30-19(11-29)27-28-21(30)16-3-1-14(23)9-18(16)25/h1-4,7,9,15H,5-6,8,10-11,26H2/t15-/m1/s1	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.01E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of DPP8 activity				Bioorg Med Chem Lett 17: 3373-7 (2007) Article DOI: 10.1016/j.bmcl.2007.03.098 BindingDB Entry DOI: 10.7270/Q2W37W04
					More data for this Ligand-Target Pair