BDBM50210671 (R)-7-(3-amino-4-(2,4,5-trifluorophenyl)butanoyl)-N-tert-butyl-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine-3-carboxamide::CHEMBL233891

SMILES: CC(C)(C)NC(=O)c1nnc2CN(CCn12)C(=O)C[C@H](N)Cc1cc(F)c(F)cc1F

InChI Key: InChIKey=BCCRFONTJXIFPI-GFCCVEGCSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50210671   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dipeptidyl peptidase VIII (Homo sapiens (Human))	BDBM50210671 ((R)-7-(3-amino-4-(2,4,5-trifluorophenyl)butanoyl)-...) Show SMILES CC(C)(C)NC(=O)c1nnc2CN(CCn12)C(=O)C[C@H](N)Cc1cc(F)c(F)cc1F Show InChI InChI=1S/C20H25F3N6O2/c1-20(2,3)25-19(31)18-27-26-16-10-28(4-5-29(16)18)17(30)8-12(24)6-11-7-14(22)15(23)9-13(11)21/h7,9,12H,4-6,8,10,24H2,1-3H3,(H,25,31)/t12-/m1/s1	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	6.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of DPP8 activity				Bioorg Med Chem Lett 17: 3373-7 (2007) Article DOI: 10.1016/j.bmcl.2007.03.098 BindingDB Entry DOI: 10.7270/Q2W37W04
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM50210671 ((R)-7-(3-amino-4-(2,4,5-trifluorophenyl)butanoyl)-...) Show SMILES CC(C)(C)NC(=O)c1nnc2CN(CCn12)C(=O)C[C@H](N)Cc1cc(F)c(F)cc1F Show InChI InChI=1S/C20H25F3N6O2/c1-20(2,3)25-19(31)18-27-26-16-10-28(4-5-29(16)18)17(30)8-12(24)6-11-7-14(22)15(23)9-13(11)21/h7,9,12H,4-6,8,10,24H2,1-3H3,(H,25,31)/t12-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	234	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of DPP4 activity				Bioorg Med Chem Lett 17: 3373-7 (2007) Article DOI: 10.1016/j.bmcl.2007.03.098 BindingDB Entry DOI: 10.7270/Q2W37W04
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 9 (Homo sapiens (Human))	BDBM50210671 ((R)-7-(3-amino-4-(2,4,5-trifluorophenyl)butanoyl)-...) Show SMILES CC(C)(C)NC(=O)c1nnc2CN(CCn12)C(=O)C[C@H](N)Cc1cc(F)c(F)cc1F Show InChI InChI=1S/C20H25F3N6O2/c1-20(2,3)25-19(31)18-27-26-16-10-28(4-5-29(16)18)17(30)8-12(24)6-11-7-14(22)15(23)9-13(11)21/h7,9,12H,4-6,8,10,24H2,1-3H3,(H,25,31)/t12-/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of DPP9 activity				Bioorg Med Chem Lett 17: 3373-7 (2007) Article DOI: 10.1016/j.bmcl.2007.03.098 BindingDB Entry DOI: 10.7270/Q2W37W04
					More data for this Ligand-Target Pair