BDBM50210898 3-(1-(3-methoxy-4-methylbenzoyl)piperidin-4-yl)benzo[d]oxazol-2(3H)-one::CHEMBL249226

SMILES: COc1cc(ccc1C)C(=O)N1CCC(CC1)n1c2ccccc2oc1=O

InChI Key: InChIKey=RUCHIAOHJYKSFE-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50210898   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM50210898 (3-(1-(3-methoxy-4-methylbenzoyl)piperidin-4-yl)ben...) Show SMILES COc1cc(ccc1C)C(=O)N1CCC(CC1)n1c2ccccc2oc1=O Show InChI InChI=1S/C21H22N2O4/c1-14-7-8-15(13-19(14)26-2)20(24)22-11-9-16(10-12-22)23-17-5-3-4-6-18(17)27-21(23)25/h3-8,13,16H,9-12H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	270	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Biovitrum AB Curated by ChEMBL					Assay Description Inhibition of human 11betaHSD1 by SPA				Bioorg Med Chem Lett 17: 3421-5 (2007) Article DOI: 10.1016/j.bmcl.2007.03.083 BindingDB Entry DOI: 10.7270/Q2GX4B72
					More data for this Ligand-Target Pair