BDBM50211156 2-biphenyl-4-yl-N-(2-dimethylamino-ethyl)-N-{(R)-1-[3-(4-fluoro-phenyl)-4-oxo-3,4-dihydro-quinazolin-2-yl]-ethyl}-acetamide::CHEMBL425824

SMILES: C[C@@H](N(CCN(C)C)C(=O)Cc1ccc(cc1)-c1ccccc1)c1nc2ccccc2c(=O)n1-c1ccc(F)cc1

InChI Key: InChIKey=HSGWCZXIIMAGHE-XMMPIXPASA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50211156   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
chemokine (C-X-C motif) receptor 3 (Homo sapiens (Human))	BDBM50211156 (2-biphenyl-4-yl-N-(2-dimethylamino-ethyl)-N-{(R)-1...) Show SMILES C[C@@H](N(CCN(C)C)C(=O)Cc1ccc(cc1)-c1ccccc1)c1nc2ccccc2c(=O)n1-c1ccc(F)cc1 Show InChI InChI=1S/C34H33FN4O2/c1-24(33-36-31-12-8-7-11-30(31)34(41)39(33)29-19-17-28(35)18-20-29)38(22-21-37(2)3)32(40)23-25-13-15-27(16-14-25)26-9-5-4-6-10-26/h4-20,24H,21-23H2,1-3H3/t24-/m1/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	75	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Displacement of [125I ]IP10 from CXCR3 receptor expressed in PBMC				Bioorg Med Chem Lett 17: 3339-43 (2007) Article DOI: 10.1016/j.bmcl.2007.03.106 BindingDB Entry DOI: 10.7270/Q2VT1SXN
					More data for this Ligand-Target Pair